Results 51 to 60 of about 90,893 (356)

The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori.

open access: yesPLoS Genetics, 2023
In lepidopteran insects, dichotomous spermatogenesis produces eupyrene spermatozoa, which are nucleated, and apyrene spermatozoa, which are anucleated.
Xu Yang   +12 more
doaj   +1 more source

Novel Gene Regulation in Normal and Abnormal Spermatogenesis

open access: yesCells, 2021
Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic and epigenetic factors. With the development of new technologies (e.g., single-cell RNA sequencing), increasingly more regulatory genes related to spermatogenesis ...
Li Du   +7 more
doaj   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

open access: yesiScience, 2021
Summary: Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not clear.
Qianxing Zou   +5 more
doaj   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone   +4 more
wiley   +1 more source

Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway

open access: yesReproductive Biology and Endocrinology, 2021
Background Infertility is a common complication in obese men. Oxidative stress and testicular apoptosis play critical roles in obesity-induced spermatogenesis dysfunction.
Yang Mu   +3 more
doaj   +1 more source

Spatially Fractionated Microbeam Analysis of Tissuesparing Effect for Spermatogenesis

open access: yes, 2020
Spatially fractionated radiation therapy (SFRT) has been based on the delivery of a single high-dose fraction to a large treatment area that has been divided into several smaller fields, reducing the overall toxicity and adverse effects.
T. Butterworth, Karl   +25 more
core   +1 more source

Evolution and spermatogenesis [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2010
Sexual reproduction depends on the production of haploid gametes, and their fusion to form diploid zygotes. Here, we discuss sperm production and function in a molecular and functional evolutionary context, drawing predominantly from studies in model organisms (mice,Drosophila,Caenorhabditis elegans). We consider the mechanisms involved in establishing
Helen, White-Cooper, Nina, Bausek
openaire   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis.

open access: yes, 2010
BACKGROUND: The Y chromosome of mammals is particularly prone to accumulate genes related to male fertility. However, the high rate of molecular evolution on this chromosome predicts reduced power to the across-species comparative approach in identifying
Ricardo N Miguel   +11 more
core   +1 more source

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