Results 51 to 60 of about 121,335 (279)

Zygoparity and sex steroid hormone profiles in bluemouth Helicolenus dactylopterus [PDF]

, 2017
Two hundred and seven individuals (103 females and 104 males) of bluemouth Helicolenus dactylopterus (Scorpaeniformes, Sebastidae), a commercially important deep-water species with an unusual reproductive strategy, from the eastern Atlantic Ocean ranging
Barcellos, Brown-Peterson, Canario, Dahle, Eldridge, Grier, Grier, Guerreiro, Howell, Hureau, Kime, Kobayashi, Liley, Matsuyama, Muñoz, Muñoz, Nagahama, Rinchard, Schulz, Scott, Sequeira, Sequeira, Sequeira, Sequeira, Shimizu, Shinomiya, Takano, Vila, Wallace, West, Wourms   +30 more
core   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway

Reproductive Biology and Endocrinology, 2021
Background Infertility is a common complication in obese men. Oxidative stress and testicular apoptosis play critical roles in obesity-induced spermatogenesis dysfunction.
Yang Mu, Huang-Guan Dai, Ling-Bo Luo, Jing Yang   +3 more
doaj   +1 more source

RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster. [PDF]

, 2019
Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that specific satellite RNAs are required ...
Allshire, Brown, Cai, Chen, Demarco, Dernburg, Ding, Eren-Ghiani, Ferree, Herbert, Hoskins, Hoskins, Jagannathan, Jain, Jandura, Jayaramaiah Raja, Johnson, Kaessmann, Kelemen, Kost, Larracuente, Legendre, Lohe, Lohe, McKee, McNulty, Ni, Nicholson, Pathak, Rathke, Rathke, Rinn, Rošić, Shirai, Shpiz, Steinhauer, Strom, Sun, Velazquez Camacho, Wei, White-Cooper, White-Cooper, Yap, Yuan, Zhu   +44 more
core   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Epi-mutations for spermatogenic defects by maternal exposure to di(2-ethylhexyl) phthalate

eLife, 2021
Exposure to environmental factors during fetal development may lead to epigenomic modifications in fetal germ cells, altering gene expression and promoting diseases in successive generations.
Yukiko Tando, Hitoshi Hiura, Asuka Takehara, Yumi Ito-Matsuoka, Takahiro Arima, Yasuhisa Matsui   +5 more
doaj   +1 more source

Testosterone and androstenedione concentrations in human testis and epididymis during the first two years of life [PDF]

, 1983
Testosterone and androstenedione were measured in testicular and epididymal tissue of 37 previously healthy infants between 1 and 24 months of age who died suddenly. In half of the patients elevated plasma levels of cortisol and androstenedione suggested
Bidlingmaier, F., Dörr, H. G., Eisenmenger, Wolfgang, Knorr, D., Kuhnle, U.   +4 more
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Application of testicular organ culture system for the evaluation of spermatogenesis impairment

Scientific Reports
Recently, it was reported that a testicular organ culture system (TOCS) using polydimethylsiloxane (PDMS) chips with excellent oxygen permeability and biocompatibility, called the PDMS-chip ceiling (PC) method, enables improved spermatogenesis efficiency.
Hideaki Nakagiri, Takehiko Ogawa, Naohiro Ikeda, Shimpei Terasaka, Yuko Nukada, Masaaki Miyazawa   +5 more
doaj   +1 more source

Effects of dioxins on animal spermatogenesis: A state-of-the-art review

Frontiers in Reproductive Health, 2022
The male reproductive system is especially affected by dioxins, a group of persistent environmental pollutants, resulting in irreversible abnormalities including effects on sexual function and fertility in adult males and possibly on the development of ...
Walaa Faiad, Chadi Soukkarieh, Denis J. Murphy, Abdulsamie Hanano   +3 more
doaj   +1 more source