Results 31 to 40 of about 90,893 (356)

Oestrogens and spermatogenesis [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2010
The role of oestrogens in male reproductive tract physiology has for a long time been a subject of debate. The testis produces significant amounts of oestrogenic hormones, via aromatase, and oestrogen receptors (ERs)α (ESR1) and ERβ (ESR2) are selectively expressed in cells of the testis as well as the epididymal epithelium, depending upon species ...
Carreau, Serge, Hess, Rex A.
openaire   +4 more sources

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis [PDF]

, 2015
A critical aspect of mammalian gametogenesis is the reprogramming of genomic DNA methylation. The catalytically inactive adaptor Dnmt3L is essential to ensuring this occurs correctly, but the mechanism by which it functions is unclear.
Robert J. Schmitz, Chad E. Niederhuth, Ooi, Steen KT, Stathopoulou, A, Richard G. Jenner, Steen K.T. Ooi, de Rooij, Dirk G, Tuna, Salih, Vlachogiannis, Georgios, Niederhuth, CE, Viiri, Keijo, Niederhuth, Chad E, Schmitz, RJ, Jenner, Richard G., Jenner, Richard G,, Vlachogiannis, G, Keijo Viiri, Tuna, S, Ooi, SK, Stathopoulou, Athanasia, Jenner, RG, Ooi, Steen K.T., de Rooij, DG, Dirk G. de Rooij, Schmitz, Robert J, de Rooij, Dirk G., Athanasia Stathopoulou, Salih Tuna, Niederhuth, Chad E., Schmitz, Robert J., Viiri, K, Ooi, Steen K. T., Georgios Vlachogiannis   +32 more
core   +1 more source

Multipathway synergy promotes testicular transition from growth to spermatogenesis in early-puberty goats

BMC Genomics, 2020
Background The microscopic process of postnatal testicular development in early-puberty animals is poorly understood. Therefore, in this study, 21 male Yiling goats with average ages of 0, 30, 60, 90, 120, 150 and 180 days old (each age group comprised ...
Dongdong Bo, Xunping Jiang, Guiqiong Liu, Feng Xu, Ruixue Hu, Teketay Wassie, Yuqing Chong, Sohail Ahmed, Chenhui Liu, Shishay Girmay   +9 more
doaj   +1 more source

Genes Regulating Spermatogenesis and Sperm Function Associated With Rare Disorders

Frontiers in Cell and Developmental Biology, 2021
Spermatogenesis is a cell differentiation process that ensures the production of fertilizing sperm, which ultimately fuse with an egg to form a zygote.
Emma Linn, Lillian Ghanem, Hanisha Bhakta, Cory Greer, Matteo Avella   +4 more
doaj   +1 more source

Testicular miRNAs in relation to spermatogenesis, spermatogonial stem cells and cancer/testis genes

Scientific African, 2019
The process of spermatogenesis in human involves three organized biological processes, through which spermatogonia cells undergo mitosis, meiosis and finally differentiation into mature spermatozoa.
Maryam Beigom Mobasheri, Kehinde Adebayo Babatunde   +1 more
doaj   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M., Ana Monteiro, Abel Margaret, Margaret Abel, Peter J. O’Shaughnessy (171628), O’Shaughnessy Peter J., Monteiro, A., O'Shaughnessy, P.J., Ana Monteiro (171632), Peter J O'Shaughnessy, Margaret Abel (171636), Monteiro Ana   +11 more
core   +1 more source

Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]

, 2010
Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel, Abel, M, Ellis, Peter J.I., Dunmore, B., Bauer, Johann W., Griffin, Darren K.   +5 more
core   +1 more source

Gene expression profiles of mouse spermatogenesis during recovery from irradiation

Reproductive Biology and Endocrinology, 2009
Background Irradiation or chemotherapy that suspend normal spermatogenesis is commonly used to treat various cancers. Fortunately, spermatogenesis in many cases can be restored after such treatments but knowledge is limited about the re-initiation ...
Skakkebæk Niels E, Kobayashi Shinichi, Iwamoto Teruaki, Nielsen John E, Tanaka Masami, Shah Fozia J, Leffers Henrik, Almstrup Kristian   +7 more
doaj   +1 more source

In Vitro Spermatogenesis in Explanted Adult Mouse Testis Tissues. [PDF]

PLoS ONE, 2015
Research on in vitro spermatogenesis is important for elucidating the spermatogenic mechanism. We previously developed an organ culture method which can support spermatogenesis from spermatogonial stem cells up to sperm formation using immature mouse ...
Takuya Sato, Kumiko Katagiri, Kazuaki Kojima, Mitsuru Komeya, Masahiro Yao, Takehiko Ogawa   +5 more
doaj   +1 more source

Multi-omics analysis reveals that iron deficiency impairs spermatogenesis by gut-hormone synthesis axis

Ecotoxicology and Environmental Safety, 2022
Considering that research has mainly focussed on how excessive iron supplementation leads to reproductive cytotoxicity, there is a lack of in-depth research on reproductive system disorders caused by iron deficiency. To gain a better understanding of the
Fa-Li Zhang, Shuai Yuan, Pei-Yu Dong, Hao-Hai Ma, Massimo De Felici, Wei Shen, Xi-Feng Zhang   +6 more
doaj   +1 more source