Results 201 to 210 of about 46,058 (304)

Machine learning‐based classification of varicocoele grading: A promising approach for diagnosis and treatment optimization

open access: yesAndrology, EarlyView.
Abstract Background Varicocoele is a correctable cause of male infertility. Although physical examination is still being used in diagnosis and grading, it gives conflicting results when compared to ultrasonography‐based varicocoele grading. Objectives We aimed to develop a multi‐class machine learning model for the grading of varicocoeles based on ...
Mehmet Vehbi Kayra   +6 more
wiley   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

open access: yesAndrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert   +10 more
wiley   +1 more source

Benchmarks defining high‐quality sperm in the common marmoset (Callithrix jacchus)

open access: yesAndrology, EarlyView.
Abstract Background Common marmosets (Callithrix jacchus) are increasingly recognized as valuable nonhuman primates (NHPs) for biomedical research due to their small size and short reproductive cycle and lifespan relative to other NHP species. Maximizing the utility of captive research marmosets, including genetically manipulated animals, will require ...
Niloofar Sadeghi   +4 more
wiley   +1 more source

Replantation following complete penile amputation: Summary of perioperative experience and treatment strategies

open access: yesAndrology, EarlyView.
Abstract Introduction To date, there are only case reports of penile amputation, a rare urological emergency with a low‐treatment successful rate, and there are still no advanced, detailed surgical or perioperative treatment plans. Effective treatments for these rare diseases are urgently needed.
Hanchao Liu   +14 more
wiley   +1 more source

Dexamethasone is a regulator of clock genes in testicular peritubular cells

open access: yesAndrology, EarlyView.
Abstract Background We recently found that peritubular cells of the human testis are a dominant site of expression of the glucocorticoid receptor (GR; encoded by NR3C1). Activation of GR by dexamethasone (Dex) strongly influences the phenotype of cultured human testicular peritubular cells (HTPCs), causing massive changes of their proteome and ...
Harald Welter   +11 more
wiley   +1 more source

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