Results 31 to 40 of about 23,426 (253)

Flow Cytometry: A New Approach for Indirect Assessment of Sperm Protamine Deficiency [PDF]

International Journal of Fertility and Sterility, 2010
Background Flow cytometry (FCM) has been extensively used to study mammalian sperm in the areas of clinical andrology and reproductive toxicology. FCM provides a powerful advantage over microscopy technique in terms of rapid accurate and reproducible ...
Marziyeh Tavalaee, Abbas Kiani, Maryam Arbabian, Mohammad Reza Deemeh, Mohammad Hossein Nasr Esfahani   +4 more
doaj   +1 more source

Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu, Yan Lu, Takuro Kobayashi, Tsuyoshi Hachiya, Haruhiko Wakita, Yiming Jin, Yasunari Tanaka, Yoshihiro Ikehata, Masayoshi Nagata, Hisamitsu Ide, Shigeo Horie   +10 more
wiley   +1 more source

Treatment Response and Outcomes of Prostate Cancer Patients Carrying the Germline MMS22L F722fs Mutation

The Prostate, EarlyView.
ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama, Violet A. Daniels, Marta Gielzak, Alex Brame, Misop Han, Li Jia, Jianfeng Xu, Tamara L. Lotan, Mario A. Eisenberger, Catherine H. Marshall, Patrick C. Walsh, William B. Isaacs, Jun Luo   +12 more
wiley   +1 more source

Genomic and Clinical Impact of Smoking on Therapeutic Outcomes in Prostate Cancer: A Public Databases Analysis

The Prostate, EarlyView.
ABSTRACT Background In prostate cancer (PCa), smoking history is associated with more aggressive clinicopathological features, reduced efficacy of androgen deprivation therapy, and poorer overall survival (OS). However, its impact on survival outcomes in patients receiving taxane chemotherapy, poly ADP‐ribose polymerase inhibitor (PARPi), or immune ...
Tomoya Hatayama, Yohei Sekino, Go Kobayashi, Kazuma Yukihiro, Yoshinori Nakano, Shinsaku Tasaka, Naofumi Nomura, Yuki Kohada, Kenshiro Takemoto, Miki Naito, Shunsuke Miyamoto, Kohei Kobatake, Hiroyuki Kitano, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Nobuyuki Hinata   +16 more
wiley   +1 more source

Eponyms in andrology [PDF]

Basic and Clinical Andrology, 2014
Andrology is the study of male reproductive health, its associated medicines, and biology, including functions and diseases that are specific to men, especially with regard to the reproductive organs. This concise report discusses the eponyms that are encountered in andrological literature.
Al Aboud, Khalid, Al Aboud, Daifullah, Munshi, Sameer, Halawi, Ali   +3 more
openaire   +2 more sources

Algorithm of ancient Ayurveda method of semen analysis and integrative approach toward male infertility

Indian Journal of Health Sciences and Biomedical Research KLEU, 2016
Ayurveda scientifically described as andrology (Vajikarana) incorporates semen morphology in normal and pathological conditions, as 8-fold pathological condition and therapy are based on them. Morphological and physicochemical evaluation methods of semen
Sreenivasa Prasad Buduru, Giridhar Vedantam   +1 more
doaj   +1 more source

Immunological microenvironment in the testis

Reproductive Medicine and Biology, 2020
Background The testis is specific in that it produces haploid germ cells of which autoantigens newly appear long after the neonatal immune tolerance. Under normal condition, these autoantigens are protected by the blood‐testis barrier formed by Sertoli ...
Ning Qu, Yuki Ogawa, Miyuki Kuramasu, Kenta Nagahori, Kou Sakabe, Masahiro Itoh   +5 more
doaj   +1 more source

External Validation of the Martini‐Klinik Nomogram Predicting the Indication for Adjuvant Radiation Therapy According to EAU Guidelines Among Patients With High‐Risk Prostate Cancer After Radical Prostatectomy

The Prostate, EarlyView.
ABSTRACT Objective To externally validate the Martini‐Klinik nomogram based on patient and clinical tumor characteristics predicting the indication for adjuvant radiation therapy after radical prostatectomy according to guideline recommendations of the European Association of Urology (EAU) in high‐risk prostate cancer patients treated with radical ...
Carolin Siech, Tonio Brüggemann, Quynh Chi Le, Benedikt Lauer, Clara Humke, Felix Preisser, Tobias Maurer, Maximilian Kriegmair, Markus Graefen, Thomas Steuber, Mike Wenzel, Felix K. H. Chun, Philipp Mandel   +12 more
wiley   +1 more source

Isolation and characterization of human spermatogonial stem cells

Reproductive Biology and Endocrinology, 2011
Background To isolate and characterization of human spermatogonial stem cells from stem spermatogonium. Methods The disassociation of spermatogonial stem cells (SSCs) were performed using enzymatic digestion of type I collagenase and trypsin.
Liu Shixue, Tang Ziwei, Xiong Tao, Tang Wei   +3 more
doaj   +1 more source

Corticosteroid Use and Risk of Adverse Events in Metastatic Hormone‐Sensitive Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Among the approved therapies for metastatic hormone‐sensitive prostate cancer (mHSPC), abiraterone and docetaxel are administered concomitantly with corticosteroids. This study evaluated the association between corticosteroid use and risk of adverse events among patients with mHSPC. Methods We conducted an observational cohort study
Umang Swami, Qiujun Shao, Tamuno Alfred, Maelys Touya, Frank Cao, Pinal Kamdar, Jasmina Ivanova, Johanna Celli, David Nimke   +8 more
wiley   +1 more source