Results 71 to 80 of about 50,976 (393)

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source

Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene

Advanced Science, EarlyView.
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan, Shumin Zhou, Jiaming Zhou, Guanghui Zhang, Jingshou Chen, Rui Liu, Kuan Sun, Sisi Li, Wenjing Xiong, Yujiao Wen, Jianzhong Sheng, Yu Zhang, Jingchao Ren, Youjiang Li, Hefeng Huang, Chen Zhang   +15 more
wiley   +1 more source

Flow Cytometry: A New Approach for Indirect Assessment of Sperm Protamine Deficiency [PDF]

International Journal of Fertility and Sterility, 2010
Background Flow cytometry (FCM) has been extensively used to study mammalian sperm in the areas of clinical andrology and reproductive toxicology. FCM provides a powerful advantage over microscopy technique in terms of rapid accurate and reproducible ...
Marziyeh Tavalaee, Abbas Kiani, Maryam Arbabian, Mohammad Reza Deemeh, Mohammad Hossein Nasr Esfahani   +4 more
doaj   +1 more source

Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity [PDF]

, 2014
STUDY QUESTION: Can we identify compound(s) with reported phosphodiesterase inhibitor (PDEI) activity that could be added to human spermatozoa in vitro to enhance their motility without compromising other sperm functions?
Alasmari, Alasmari, Baker, Barratt, Baxendale, Bjorndahl, Christopher L.R. Barratt, Comhaire, Conti, Cooper, David, Fisch, Ford, Francis, Glenn, Harrison, HFEA, Horvath, Houslay, Huacuja, Hull, Hunnicutt, Irvine, Ivic, Lefièvre, Lefièvre, Lefièvre, Linda Lefièvre, Lorna Frame, Martin, Mortimer, Mrsny, Nassar, Negri, O'Connell, Oladipo A. Madamidola, Paul G. Wyatt, Publicover, Richter, Sarah J. Martins Da Silva, Sean G. Brown, Sousa, Steve Tardif, Stone, Tesarik, Tomlinson, Tomlinson, Torres-Flores, Tournaye, Tournaye, Van der Steeg, Wang, Yang, Yovich, Yovich   +54 more
core   +5 more sources

Hi‐LabSpermTracking: A Novel and High‐Quality Sperm Tracking Dataset with an Advanced Ensemble Detection and Tracking Approach for Real‐World Clinical Scenarios

Advanced Intelligent Systems, EarlyView.
This study presents Hi‐LabSpermTracking, a long‐duration, expert‐annotated sperm motility dataset for detection and tracking. It evaluates You Only Look Once version 8, Real‐Time Detection Transformer, and Simple Online and Realtime Tracking with a Deep Association Metric in three scenarios. The mean ensemble method improves tracking performance. Sperm
Abdulsamet Aktas, Gorkem Serbes, Hakkı Uzun, Merve Huner Yigit, Nizamettin Aydin, Hamza Osman Ilhan   +5 more
wiley   +1 more source

Clinical use of hyaluronic acid in andrology: A review

Andrology, 2021
Hyaluronic acid is a glycosaminoglycan widely used in the fields of orthopedics, ophthalmology, and aesthetic medicine due to its significant ability to reduce the synthesis of pro‐inflammatory proteins and its activity against oxidative stress, a ...
A. Zucchi, F. Scroppo, P. Capogrosso, A. Salonia, Jacopo Duante, V. Bini, G. Liguori, R. Bartoletti   +7 more
semanticscholar   +1 more source

Pregnancy via Testicular Sperm Extraction for Anejaculation After Neuroblastoma Surgery

IJU Case Reports, EarlyView.
ABSTRACT Background Surgical treatment of a neuroblastoma, a malignant tumor of the sympathetic nervous system, may result in ejaculatory disorder. There are no reports examining ejaculation disorders after neuroblastoma surgery. Case Presentation The patient was a 31‐year‐old Japanese male who had undergone surgery for neuroblastoma of the abdomen at ...
Jurii Karibe, Teppei Takeshima, Daiji Takamoto, Takashi Kawahara, Kimito Osaka, Jun‐ichi Teranishi, Kazuhide Makiyama, Hiroji Uemura, Yasushi Yumura   +8 more
wiley   +1 more source

Genomic biomarkers in prostate cancer. [PDF]

, 2018
Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer.
Cooperberg, Matthew R, Feng, Felix Y, Kornberg, Zachary, Spratt, Daniel E   +3 more
core  

Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment [PDF]

, 2015
The aim of this study was to investigate sperm DNA damage induced by chemo- and radiotherapy in patients with testicular cancer to provide data on the extent and persistence of nuclear damage that might affect individual reproductive potential.
F. Rizzo, G. Leter, GALLO, MARIAGRAZIA, GANDINI, Loredana, LENZI, Andrea, LOMBARDO, Francesco, M. Spano, PAOLI, Donatella   +7 more
core   +1 more source

Update in Andrology [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2007
Context: This is an invited review based on a presentation at the 2007 Annual Scientific Meeting of The Endocrine Society. Objective: The objective of the review was to highlight a selection of the most important peer-reviewed papers in andrology published over the last 1–2 yr.
openaire   +1 more source