Results 91 to 100 of about 342 (115)
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Analysis of the Interactions of Amphotericin B with the Leishmania Plasma Membrane Using EPR Spectroscopy.

Journal of Physical Chemistry B, 2020
Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to study the interactions of amphotericin B (AmB) with the plasma membrane of Leishmania amazonensis promastigotes, erythrocytes, and J774 macrophages.
Laís Alonso   +3 more
semanticscholar   +1 more source

CAR, the continuously advancing receptor, in drug metabolism and disease.

Current drug metabolism, 2005
The detoxification and elimination of potentially toxic foreign and endogenous compounds depends on the concerted action of xenobiotic metabolizing enzymes.
M. Qatanani, D. Moore
semanticscholar   +1 more source

The role of 5a-reduction in steroid hormone physiology

, 2001
A role for 5α-reduction in androgen physiology was first established with the recognition that dihydrotestosterone, the 5α-reduced metabolite of testosterone, is formed in many androgen target tissues, binds to the androgen receptor with greater affinity
Jean D. Wilson
semanticscholar   +1 more source

Spin-label studies of lipid-protein interactions in (Na+,K+)-ATPase membranes from rectal glands of Squalus acanthias.

Biochemistry, 1985
Lipid-protein interactions in (Na+,K+)-ATPase-rich membranes from the rectal gland of Squalus acanthias have been studied by using spin-labeled lipids in conjunction with electron spin resonance (ESR) spectroscopy. Lipid-protein associations are revealed
M. Esmann, Anthony Watts, D. Marsh
semanticscholar   +1 more source

Stoichiometry and specificity of lipid-protein interaction with myelin proteolipid protein studied by spin-label electron spin resonance.

Biochemistry, 1984
The interaction of spin-labeled lipids with the myelin proteolipid apoprotein in complexes with dimyristoylphosphatidylcholine of varying lipid/protein ratios has been studied with electron spin resonance spectroscopy.
P. Brophy, L. Horváth, D. Marsh
semanticscholar   +1 more source

Novel cell-based reporter assay system using epitope-tagged protein for the identification of agonistic ligands of constitutive androstane receptor (CAR).

Drug Metabolism and Pharmacokinetics, 2013
Constitutive androstane receptor (CAR) plays vital roles in multiple liver functions including xenobiotic and energy metabolisms, and also in hepatocarcinogenesis.
J. Imai, Y. Yamazoe, K. Yoshinari
semanticscholar   +1 more source

Sum frequency generation vibrational spectroscopy of cholesterol in hybrid bilayer membranes.

Journal of Physical Chemistry B, 2013
The assignment of the vibrational spectrum of cholesterol is surprisingly incomplete for such a fundamental molecule. To improve our understanding, a new investigation of the spectra of cholesterol in the C-H stretching region has been undertaken using ...
P. Kett, M. Casford, P. Davies
semanticscholar   +1 more source

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