Results 21 to 30 of about 342 (115)
Molecular Endocrinology, 2005 Activating signal cointegrator-2 (ASC-2) is a recently isolated transcriptional coactivator protein for a variety of different transcription factors, including many members of the nuclear receptor superfamily.
E. Choi +5 more
semanticscholar +1 more source
Toxicological Sciences, 2006 To characterize the function of constitutive active/androstane receptor (CAR) in aquatic mammals, CAR complementary DNA (cDNA) was cloned from the liver of Baikal seal (Pusa sibirica) from Lake Baikal, Russia, and the messenger RNA (mRNA) expression ...
H. Sakai +7 more
semanticscholar +1 more source
NONSTEROIDAL ANTIRHEUMATICS AND HYPERTENSION [PDF]
, 2011 Nesteroidni antireumatici (NSAR) skupina su lijekova koji se najčešće rabe u kliničkoj medicini, čine 4–9% svih propisanih lijekova, a bolesnici koji ih uzimaju izloženi su mogućim nuspojavama.
Bojan Jelaković, Krešimir Galešić
core +1 more source
Computing Network of Diseases and Pharmacological Entities through the Integration of Distributed Literature Mining and Ontology Mapping [PDF]
, 2011 The proliferation of -omics (such as, Genomics, Proteomics) and -ology (such as, System Biology, Cell Biology, Pharmacology) have spawned new frontiers of research in drug discovery and personalized medicine.
Faisal, Fazle Elahi
core +1 more source
XENOBIOTIC REGULATION OF THE ATP BINDING CASSETTE TRANSPORTER ABCB6 AND ITS SIGNIFICANCE TO HEPATIC HEME HOMEOSTASIS [PDF]
, 2013 Heme is indispensable for mammalian life. It is an essential component of numerous heme proteins, with functions including oxygen transport and storage, energy metabolism, drug and steroid metabolism and signal transduction.
Chavan, Hemantkumar Dilip
core
An investigation into the analysis of ecdysones and other steroid hormones [PDF]
, 1975 As an aid to the analysis of ecdysones (arthropod moulting hormones), an investigation has been carried out to find an efficient and sensitive method for determining them by chromatography.
Poole, Colin Frank
core +1 more source
World Journal of Gastroenterology, 2007 AIM To ascertain whether constitutive androstane receptor (CAR) activation by 1,4-bis-[2-(3,5,-dichloropyridyloxy)] benzene (TCPOBOP) modulates steatohepatitis in the methionine choline-deficient (MCD) diet-fed animal.
E. Baskin-Bey +4 more
semanticscholar +1 more source
Molecular Endocrinology, 2003 The mouse constitutive androstane receptor (CAR) is a unique member of the nuclear receptor superfamily, for which an inverse agonist, the testosterone metabolite 5alpha-androstan-3alpha-ol (androstanol), and an agonist, the xenobiotic 1,4-bis[2-(3, 5 ...
Teemu Andersin +2 more
semanticscholar +1 more source
Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity.
World Journal of Gastroenterology, 2005 AIM To investigate the precise roles of CAR in CCl(4)-induced acute hepatotoxicity. METHODS To prepare an acute liver injury model, CCl(4) was intraperitoneally injected in CAR+/+ and CAR-/- mice.
Y. Yamazaki +5 more
semanticscholar +1 more source
Nongenomic effects of steroids on the nicotinic acetylcholine receptor.
Kidney International, 2000 A fast signaling mode of natural and synthetic steroids is exerted on some ion channels and cell-surface receptors. This activity contrasts with their classic mode of action, via intracellular receptors.
Francisco J. Barrantes +4 more
semanticscholar +1 more source