Results 111 to 120 of about 27,928 (247)

Nivolumab Induced Lethal Aplastic Anemia in a Patient with Metastatic Melanoma

Case Reports in Oncology, 2019
Nivolumab is an active treatment in patients with metastatic melanoma. We report a case of a patient with metastatic malignant melanoma who was given nivolumab as an advanced-line treatment.
Keren Rouvinov, Karen Nalbandyan, Victor Kozlov, Nir Peled, Alexander Yakobson   +4 more
doaj   +1 more source

A Proposed Clinical Diagnostic Framework for Short Telomere Syndrome

Clinical Genetics, Volume 110, Issue 2, Page 139-149, August 2026.
We propose a phenotype‐based diagnostic framework for short telomere syndrome that integrates age‐adjusted telomere length, phenotypic manifestations, and genetic findings, where available. The framework is intended to guide clinical evaluation, longitudinal surveillance, and individualized management while acknowledging limitations in current telomere
Andrew Courtwright, Richard A. King, Jennie Vagher, Cate T. Levy, Juan Gallegos F. Orozco, Luis FZ Batista, Afaf Osman, Srinivas Tantavahi, Mary Beth Scholand   +8 more
wiley   +1 more source

Acquired aplastic anemia in children [PDF]

, 2009
Catedra Pediatrie nr.2 USMF „Nicolae Testemiţanu”Aplastic anemia in children is one of the major problems of pediatric haematology with imprevisible evolution and consequences followed by complications due to pancytopenia and immune supresion.
Ţurea, Valentin, Popa, Olga
core  

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 795-806, August 2026.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

Sex-Biased CD3ζ 3ʹ-UTR SNP Increased Incidence Risk in Aplastic Anemia [PDF]

Lixing Guo,1,* Yuping Zhang,2,* Xiaoen Liu,3,* Yankai Xiao,3,* Weifeng Luo,4 Su Fang,5 Yan Li,6 Jing Lai,7 Yangqiu Li,3,7 Bo Li3 1Department of Hematology and Oncology, The Fifth Affiliated Hospital of Jinan University, Heyuan, People’s ...
Liu X, Guo L, Li Y, Lai J, Zhang Y, Xiao Y, Luo W, Fang S, Li B   +8 more
core  

Serum stem cell factor levels in patients with aplastic anemia [PDF]

, 1994
Immune suppression of hematopoiesis has been implicated in the pathogenesis of acquired aplastic anemia. Similarly, abnormalities of T cells and bone marrow stromal cells have been reported in aplastic anemia, as has abnormal cytokine production.
Nimer, S D, Wolin, M J, Golde, D W, Leung, D H   +3 more
core   +2 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Pregnancy-associated Aplastic Anemia: Case Report [PDF]

, 2010
Aplastic anemia in pregnancy is a rare condition with high maternal morbidity and mortality rates. Intensive hematological support during antenatal course remains the mainstay of the therapy.
Kale, Ahmet, Fatmanur, Hancer, Kuyumcuoglu, Umur   +2 more
core  

Successful Surgical Management of Chronic Subdural Hematoma in a Patient With Severe Thrombocytopenia due to Aplastic Anemia: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT This case report describes the successful surgical management of a chronic subdural hematoma (CSDH) in a 45‐year‐old male with severe aplastic anemia (AA) and severe thrombocytopenia. The patient presented with worsening headaches, and imaging confirmed a progressive CSDH with midline shift. Despite a platelet count of 22 × 109/L, preoperative
Zhenghao Fu, Jiankan Lu, Xinqing Deng
wiley   +1 more source