Results 91 to 100 of about 334,579 (212)

Child with aplastic anemia: Anesthetic management

Saudi Journal of Anaesthesia, 2012
Aplastic anemia is a rare heterogeneous disorder of hematopoietic stem cells causing pancytopenia and marrow hypoplasia with the depletion of all types of blood cells.
Manpreet Kaur, Babita Gupta, Aanchal Sharma, Sanjeev Sharma   +3 more
doaj   +1 more source

Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia

New England Journal of Medicine, 2022
Régis Peffault de Latour, A. Kulasekararaj, S. Iacobelli, Sofie R. Terwel, Riley Cook, M. Griffin, C. Halkes, C. Récher, F. Barraco, E. Forcade, J. Vallejo, B. Drexler, J. Mear, Alexander Smith, E. Angelucci, R. Raymakers, M. D. de Groot, É. Daguindau, E. Nur, W. Barcellini, N. Russell, L. Terriou, A. Iori, U. La Rocca, A. Sureda, I. Sánchez-Ortega, B. Xicoy, I. Jarque, J. Cavenagh, F. Sicre de Fontbrune, S. Marotta, T. Munir, J. Tjon, S. Tavitian, A. Praire, L. Clément, Florence Rabian, L. Marano, A. Hill, E. Palmisani, P. Muus, F. Cacace, C. Frieri, M. V. van Lint, J. Passweg, J. Marsh, G. Socié, G. Mufti, C. Dufour, A. Risitano   +49 more
semanticscholar   +1 more source

The Pathophysiology of Acquired Aplastic Anemia: Current Concepts Revisited

Hematology/Oncology Clinics of North America, 2018
Idiopathic acquired aplastic anemia is a rare, life-threatening bone marrow failure syndrome characterized by cytopenias and hypocellular bone marrow. The pathophysiology is unknown; the most favored model is of a dysregulated immune system leading to ...
M. Schoettler, D. Nathan
semanticscholar   +1 more source

Clonal Dynamics of GPI‐Deficient Cells in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH): A Retrospective Follow‐Up Analysis

European Journal of Haematology, EarlyView.
ABSTRACT This retrospective, single‐center study aimed to characterize clonal dynamics of GPI‐deficient cells in patients with paroxysmal nocturnal hemoglobinuria (PNH) or PNH/aplastic anemia (AA) syndrome using multiparameter flow cytometry including FLAER.
Sandra M. Frey, Friederike Poppenborg, Ute Schmücker, Nicole Preising, H. Christian Reinhardt, Alexander Röth, Ferras Alashkar   +6 more
wiley   +1 more source

Perspective and Experience of Patients with Aplastic Anemia on Medication Adherence

Patient Preference and Adherence, 2023
Hangting Li,1,* Xiaolian Wu,1,* Jiaoni Shen,2 Shuhui Lou2 1Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, People’s Republic of China ...
Li H, Wu X, Shen J, Lou S
doaj  

Exome sequencing identifies MPL as a causative gene in familial aplastic anemia

Haematologica, 2012
The primary cause of aplastic anemia remains unknown in many patients. The aim of this study was to clarify the genetic cause of familial aplastic anemia.
Amanda J. Walne, Arran Dokal, Vincent Plagnol, Richard Beswick, Michael Kirwan, Josu de la Fuente, Tom Vulliamy, Inderjeet Dokal   +7 more
doaj   +1 more source

Deep intronic ANK1 variants causing pseudo‐exon inclusion in hereditary spherocytosis: Whole‐genome sequencing and functional assessment

British Journal of Haematology, EarlyView.
Victor Marin, Alexandre Janin, Céline Renoux, Yoann Huguenin, AURAGEN consortium, Stéphanie Dulucq, Louis Lebreton, Philippe Joly, Julian Boutin   +8 more
wiley   +1 more source

Expert Consensus on the Diagnosis and Monitoring of Paroxysmal Nocturnal Hemoglobinuria (PNH): An Algorithmic Approach in an Era of New Treatments

European Journal of Haematology, EarlyView.
ABSTRACT Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder caused by a defect of glycosylphosphatidyl‐anchored proteins, leading to an uncontrolled complement‐mediated hemolysis. The advent of complement inhibitors in clinical practice radically changed patients' outcomes and survival.
Bruno Fattizzo, Monia Marchetti, Elisa Cannizzo, Arianna Gatti, Massimo Geuna, Anna Paola Iori, Maddalena Raia, Simona Sica, Francesco Buccisano   +8 more
wiley   +1 more source

Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

Journal of Hematology & Oncology, 2017
BackgroundHaploidentical donor (HID) hematopoietic stem cell transplantation (HSCT) is an alternative treatment method for severe aplastic anemia (SAA) patients lacking suitable identical donors and those who are refractory to immunosuppressive therapy ...
Lanping Xu, Song Jin, Shun-Qing Wang, Ling-Hui Xia, H. Bai, Su-Jun Gao, Qifa Liu, Jian-min Wang, Xin Wang, Ming Jiang, Xi Zhang, Depei Wu, Xiao-jun Huang   +12 more
semanticscholar   +1 more source

Long‐term efficacy and safety of romiplostim plus immunosuppressive therapy as first‐line treatment in patients with aplastic anaemia: 2‐year interim analysis of observational study of two clinical trials

British Journal of Haematology, EarlyView.
Jong Wook Lee, Kohei Hosokawa, Jun Ho Jang, Naoshi Obara, Masashi Sawa, Kensuke Usuki, Gaku Oshikawa, Masahiro Kizaki, Koji Nagafuji, Ting‐An Lin, Hitoshi Hanamoto, Yeung‐Chul Mun, Toshiro Kawakita, Kazunori Imada, June‐Won Cheong, Sung‐Soo Park, Takayuki Tabayashi, Masaru Gamou, Kenta Murotani, Hirohito Yamazaki   +19 more
wiley   +1 more source