Results 71 to 80 of about 42,507 (225)

Altered expression of the TCR signaling related genes CD3 and FcεRIγ in patients with aplastic anemia [PDF]

, 2012
Background Aplastic anemia (AA) is characterized by pancytopenia and bone marrow hypoplasia, which results from immune-mediated hematopoiesis suppression.
AM Wegener, B Malissen, Bo Li, C Dufour, E Sloand, ED Zanders, EE Solomou, EJ Enyedy, EN Kersh, F Zhou, H Clevers, H Murata, JM Oliver, JP Maciejewski, K Amemiya, K Kaito, KJ Livak, L Ciszak, L Shiue, LA Pitcher, Lijian Yang, ME Call, ME Call, N Taylor, NC Zoumbos, NC Zoumbos, NS Young, NS Young, S Chen, S Koyasu, S Krishnan, SD Thompson, Shaohua Chen, Sichu Liu, Su Fang, T Kato, Xiuli Wu, Y Li, Yangqiu Li, Yuzhe Niu, Zhi Yu, ZM Sun   +41 more
core   +2 more sources

Long‐Term Clinical and Molecular Dynamics in Hypoplastic Myelodysplastic Neoplasia Treated With Immunosuppressive Therapy

European Journal of Haematology, EarlyView.
ABSTRACT Myelodysplastic neoplasia (MDS) comprises heterogeneous clonal hematologic disorders characterized by peripheral cytopenia, bone marrow dysplasia, and a risk of leukemic transformation. A hypoplastic variant (MDS‐h) shares features with aplastic anemia and responds to immunosuppressive therapy (IST).
Hannes Treiber, Christina Ganster, Katayoon Shirneshan, Katharina Rittscher, Elzbieta Brzuszkiewicz, Justin Hasenkamp, Wolfram Jung, Gerald Wulf, Detlef Haase   +8 more
wiley   +1 more source

APLASTIC ANEMIA ET CAUSA OF SUSPECT VIRAL HEPATITIS INFECTION: A CASE REPORT

e-Jurnal Medika Udayana, 2014
Aplastic anemia is anemia that occurs because of a failure of hematopoiesis is relatively rarebut can be life threatening. The cause of aplastic anemia itself is still largely unknown oridiopathic.
I Wayan Wawan Lismana
doaj  

Elevated serum aminotransferases in an infant with failure to thrive: A clinicopathological case report

JPGN Reports, EarlyView.
Jamie M. Klapp, Lauren Nichols, Nicholas J. Gloude, Amber Hildreth, Kathleen B. Schwarz   +4 more
wiley   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres

Haematologica, 2015
Aplastic anemia is a rare but life-threatening disorder characterized by cytopenia in at least two of the three blood lineages. A frequent feature of patients with aplastic anemia is that they have shorter telomeres than those of age-matched controls ...
Christian Bär, Nicolas Huber, Fabian Beier, Maria A. Blasco   +3 more
doaj   +1 more source

Values of Individuals With Rare Genetic Neurodevelopmental Disorders and Their Family/Caregivers in Healthcare: A Scoping Review to Inform Guideline Development

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Healthcare decision‐making for individuals with rare genetic neurodevelopmental disorders (RGNDs) associated with intellectual disabilities (ID) can be complex due to the intersection of lifelong care needs, limited medical expertise and communication barriers.
Mirthe J. Klein Haneveld, Louise Cox, Petri J. C. M. Embregts, Alistair R. Niemeijer, Martina C. Cornel, Charlotte M. W. Gaasterland, Agnies M. van Eeghen   +6 more
wiley   +1 more source

Aplastic anemia: a new complication in the recent mysterious hepatitis outbreak among children worldwide: two case reports

Journal of Medical Case Reports, 2022
Background Recently, an unknown hepatitis outbreak among children has concerned many individuals worldwide. These cases are frequently reported, mainly from Europe and other countries.
Ali Ghanei-Shahmirzadi, Hamid Reihani, Ali Abbasi-Kashkooli, Fereshteh Karbasian, Seyyed Bozorgmehr Hedayati, Mohammadreza Bordbar, Maryam Ataollahi, Seyed Mohsen Dehghani, Bita Geramizadeh   +8 more
doaj   +1 more source

The iron content of gastric juice: in relation to the cause of idiopathic hypochromic anemia [PDF]

, 1967
Non-hemin iron content in gastric juice was examined in 46 patients with various blood diseases, especially idiopathic hypochromic anemia and in 26 healthy controls. 1. The iron content in gastric juice was found to be 290 μg/ dl in healthy controls,
Kimura, Ikuro, Yamana, Masatoshi
core   +1 more source

Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim, Fatima Al Sarraf, Hana Cho, Navdeep Kumar   +3 more
wiley   +1 more source