Results 71 to 80 of about 24,700 (204)

Deep sequencing and flow cytometric characterization of expanded effector memory CD8+CD57+ T cells frequently reveals T-cell receptor Vβ oligoclonality and CDR3 homology in acquired aplastic anemia

open access: yesHaematologica, 2018
Oligoclonal expansion of CD8+ CD28− lymphocytes has been considered indirect evidence for a pathogenic immune response in acquired aplastic anemia. A subset of CD8+ CD28− cells with CD57 expression, termed effector memory cells, is expanded in several ...
Valentina Giudice   +8 more
doaj   +1 more source

Thrombocytopenia in Pregnancy: A 5‐Year Analysis of Characteristics and Practices From a Tertiary Academic Center

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Moderate‐to‐severe thrombocytopenia (platelet count < 100 × 109/L) occurs in fewer than 1% of pregnancies, posing management challenges, particularly surrounding eligibility for neuraxial anesthesia. Although recent anesthesia guidelines recommend a platelet threshold ≥ 70 × 109/L, outcomes data applying these recommendations in ...
Mackenzie E. Lemieux, Ming Y. Lim
wiley   +1 more source

Diagnosis, Diagnosis Differensial dan Penatalaksanaan Immunosupresif dan Terapi Sumsum Tulang pada Pasien Anemia Aplastik

open access: yese-Jurnal Medika Udayana, 2014
Anemia aplastic is anemia with bone marrow failure characterized by pancytopenia and at themost case with hypoplasia bone marrow. The incidence of anemia aplastic is 3 -6 case per 1million persons per year.
Thaha ..   +2 more
doaj  

Current strategies against invasive fungal infections in patients with aplastic anemia, strong power and weak weapon, a case report and review of literature

open access: yesMedical Mycology Case Reports, 2016
We report an 18 year old boy with Aplastic anemia complicated by serious fungal rhinosinusitis. Despite prompt treatment and early repeated surgical debridements, he died after about more than 6 weeks of hard challenges with fungal infections.
Omid Reza Zekavat   +6 more
doaj   +1 more source

ICSH Guidance on Bone Marrow Examination and Reporting

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber   +6 more
wiley   +1 more source

Acute lymphoblastic leukemia of childhood presenting as aplastic anemia: report of two cases

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2012
Acute lymphoblastic leukemia is the most common malignancy in pediatric patients; its diagnosis is usually easy to establish as malignant lymphoblasts invade the bone marrow and peripheral blood.
Laura Villarreal-Martínez   +4 more
doaj   +1 more source

Unsupervised Global CBC/RUO/CPD Phenotyping Identifies Haematological Clusters Enriched for Thrombocytopenia Severity and Mechanisms

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Thrombocytopenia has heterogeneous mechanisms, including peripheral destruction, consumption, and reduced marrow production. This study developed an unsupervised global complete blood count/research‐use‐only/cell population data (CBC/RUO/CPD) phenotyping model and evaluated post hoc whether thrombocytopenia severity and clinically
Mohammad A. Altememi   +5 more
wiley   +1 more source

Child with aplastic anemia: Anesthetic management

open access: yesSaudi Journal of Anaesthesia, 2012
Aplastic anemia is a rare heterogeneous disorder of hematopoietic stem cells causing pancytopenia and marrow hypoplasia with the depletion of all types of blood cells.
Manpreet Kaur   +3 more
doaj   +1 more source

Real‐world evidence on the safety and effectiveness of thrombopoietin receptor agonists in aplastic anaemia: A descriptive study using Japanese hospital administrative data

open access: yes
British Journal of Haematology, EarlyView.
Kayoko Mizuno   +6 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

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