Results 61 to 70 of about 42,507 (225)

Aplastic anemia after pediatric liver transplantation [PDF]

, 2009
A aplasia de medula é uma das mais raras (
CARNEIRO, Jorge D. A., GARANITO, Marlene P., GIBELLI, Nelson E. M., MATSUMOTO, Lucy A., SANTOS, Maria Mercês, TANNURI, Uenis   +5 more
core   +1 more source

Decoding immune‐driven erythroid failure in pure red cell aplasia

British Journal of Haematology, EarlyView.
Pure red cell aplasia (PRCA) is increasingly recognised as a T‐cell‐mediated bone marrow failure syndrome, yet its immunogenetic drivers remain poorly defined. In their paper, Yamashita et al. integrate human leucocyte antigen (HLA) typing, T‐cell receptor repertoire analysis and mutational profiling to reveal enriched HLA alleles, signal transducer ...
Federico Spataro, Vanessa Desantis, Antonio Giovanni Solimando   +2 more
wiley   +1 more source

Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia [PDF]

, 2019
Introduction Chromosomal abnormalities are frequent events in hematological malignancies. The degree of HLA compatibility between donor and recipient in hematopoietic stem cell transplantation is critical.
Breman, Amy M., Britton, Rebecca M., Cui, Connie P., Farag, Sherif S., Kashi, Zahra, Krueger-Sersen, Mary, Littrell, Courtney A., Lobashevsky, Andrew L., Martin, Russ K., Singh, Susmita, Vance, Gail H.   +10 more
core   +1 more source

Immunological features of acquired pure red cell aplasia: Specific human leucocyte antigen alleles, signal transducer and activator of transcription 3 mutations and a unique T‐cell receptor beta motif

British Journal of Haematology, EarlyView.
Summary T‐cell abnormalities have been implicated in the pathogenesis of acquired pure red cell aplasia (PRCA), particularly in its major subtypes such as idiopathic PRCA, thymoma‐associated PRCA and large granular lymphocytic leukaemia (LGLL)–associated PRCA, and the precise details remain unclear.
Naruaki Yamashita, Toru Kawakami, Shuji Matsuzawa, Shotaro Miyairi, Masae Maruyama, Fumihiro Kawakami, Shunsuke Kojima, Ryu Yanagisawa, Yumiko Higuchi, Hideki Makishima, Hideyuki Nakazawa, Fumihiro Ishida   +11 more
wiley   +1 more source

Recurrent idiopathic acute hepatitis-associated aplastic anemia/pancytopenia fourteen years after initial episode

Annals of Hepatology, 2010
Aplastic anemia following viral hepatitis is a condition well recognized in the medical literature. Although hepatitis-associated aplastic anemia is an uncommon syndrome, there are several reports in the literature describing such cases. In these reports,
Nawal Al Nahdi, Holly Wiesinger, Heather Sutherland, Eric M. Yoshida   +3 more
doaj   +1 more source

Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]

, 2010
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher, Cheema, Gurtej, Gershwin, M Eric, Naguwa, Stanley M, Powell, Christian   +4 more
core   +1 more source

APLASTIC ANEMIA [PDF]

Blood, 1948
Abstract Two cases of aplastic anemia following gold therapy are presented, bringing the total number of reported cases to 20. In one of the cases BAL was unsuccessfully used therapeutically.
WILLIAM J. FITZPATRICK, STEVEN O. SCHWARTZ   +1 more
openaire   +1 more source

High frequency of CD95+/CD45RA− regulatory T cells defines an immunosuppressive profile associated with MDS progression

British Journal of Haematology, EarlyView.
Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Romain Vazquez, Nicolas Deredec, Ismael Boussaid, Pierre Boncoeur, Camille Knosp, Amandine Houvert, Loria Zalmai, Chloe Friedrich, Carole Almire, Charles Dussiau, Lise Willems, Rudy Birsen, Justine Decroocq, Didier Bouscary, Olivier Kosmider, Shahram Kordasti, Michaela Fontenay, Yannick Simoni, Nicolas Chapuis   +18 more
wiley   +1 more source

Relapse of aplastic anemia in children after immunosuppressive therapy: a report from the Japan Childhood Aplastic Anemia Study Group

Haematologica, 2011
Background Although the therapeutic outcome of acquired aplastic anemia has improved markedly with the introduction of immunosuppressive therapy using antithymocyte globulin and cyclosporine, a significant proportion of patients subsequently relapse and ...
Takuya Kamio, Etsuro Ito, Akira Ohara, Yoshiyuki Kosaka, Masahiro Tsuchida, Hiroshi Yagasaki, Hideo Mugishima, Hiromasa Yabe, Akira Morimoto, Shouichi Ohga, Hideki Muramatsu, Asahito Hama, Takashi Kaneko, Masayuki Nagasawa, Atsushi Kikuta, Yuko Osugi, Fumio Bessho, Tatsutoshi Nakahata, Ichiro Tsukimoto, Seiji Kojima   +19 more
doaj   +1 more source

Aplastic Anemia: Clinicohaematological Features, Treatment and Outcome Analysis [PDF]

, 2011
Objective: To determine the clinicohaematological features, treatment and outcome of children diagnosed with aplastic anemia at a single institution. Study Design: Observational study.
Adil, Salman, Fidoo, Zehra, Naqvi, Muhammad Ahmed, Wali, Rabia   +3 more
core   +1 more source