Results 141 to 150 of about 334,579 (212)

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu   +6 more
wiley   +1 more source

Spontaneous remission of aplastic anemia: a retrospective analysis

open access: yesHaematologica, 2001
BACKGROUND AND OBJECTIVES: Although acquired aplastic anemia is usually a chronic disorder, a small proportion of patients with aplastic anemia was reported to recover spontaneously without specific therapy such as allogeneic bone marrow transplantation ...
JH Lee   +7 more
doaj  

Aplastic anemia - Diagnosis [PDF]

open access: yesDMW - Deutsche Medizinische Wochenschrift, 2003
K, Hohloch, L, Trümper, R, Schroers
openaire   +2 more sources

Isocitrate Dehydrogenase (IDH) Mutations in Hematological Malignancies: Epidemiology, Mechanisms, and Therapeutic Strategies

open access: yesMedComm – Future Medicine, Volume 5, Issue 3, September 2026.
IDH mutation is an important event in hematological malignancies. This review systematically integrates the basic mechanism of IDH mutations and combines it with the clinical translation of related research progress. It also discusses the application strategies of IDH inhibitors and feasible research directions, with the aim of providing a theoretical ...
Jinkun Xu, Haiying Bai, Lijuan Hu
wiley   +1 more source

A real‐world study on different initiation times and treatment durations of letermovir for cytomegalovirus prophylaxis after allogeneic haematopoietic stem cell transplantation

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 1198-1207, September 2026.
Early letermovir initiation (day 0) after allogeneic haematopoietic stem cell transplantation (allo‐HSCT) reduced early cytomegalovirus (CMV) infection and delayed first CMV DNAemia compared with later starts. Extending prophylaxis to 200 days virtually eliminated late CMV reactivation and improved 1‐year overall survival, with no grade ≥3 drug‐related
Shiyu Chen   +4 more
wiley   +1 more source

Posaconazole Target Attainment in Critically Ill Children: A 15‐Year Single‐Center Retrospective Analysis

open access: yesClinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Posaconazole is a triazole antifungal agent used for prophylaxis and treatment of invasive fungal diseases. Posaconazole has high inter‐individual variability in dose‐exposure relationship and benefits from therapeutic drug monitoring (TDM). Adult studies report particularly high rates of subtherapeutic exposure among intensive care unit (ICU)
Kathryn Pavia   +2 more
wiley   +1 more source

Cardiovascular Diseases and All‐Cause Mortality Risk in Patients With Prehypertension and Noncommunicable Diseases: Results From the Kailuan Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 9, September 2026.
ABSTRACT It remains unclear whether prehypertension combined with noncommunicable diseases (NCDs) is associate with higher risks of cardiovascular diseases (CVD) and all‐cause mortality. The study aimed to investigate the associations of prehypertension with CVD and all‐cause mortality in individuals with or without NCDs.
Ruiying Zhang   +7 more
wiley   +1 more source

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