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New England Journal of Medicine, 2018 Aplastic anemia - bone marrow failure (AA) is defined as pancytopenia with hypocellular bone marrow without signs of marrow fibrosis or of presence of abnormal cells. Recent studies showed that most of AA cases might be mediated by immune mechanisms.
Neal S Young
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The Journal of Nervous and Mental Disease, 1984
A 29-year-old married nurse with pancytopenia was discovered to be surreptitiously ingesting alkylating agents. Despite her life-threatening behavior, there was no evidence that she was psychotic, depressed, or cognitively impaired. Psychological testing was indicative of a sociopathic personality.
C V, Ford +3 more
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A 29-year-old married nurse with pancytopenia was discovered to be surreptitiously ingesting alkylating agents. Despite her life-threatening behavior, there was no evidence that she was psychotic, depressed, or cognitively impaired. Psychological testing was indicative of a sociopathic personality.
C V, Ford +3 more
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Hospital Practice, 1980
Bone marrow transplantation and androgen therapy offer some hope of survival for patients with aplastic anemia, whether the disease is idiopathic or induced by drugs or toxins.
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Bone marrow transplantation and androgen therapy offer some hope of survival for patients with aplastic anemia, whether the disease is idiopathic or induced by drugs or toxins.
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CHLORAMPHENICOL AND APLASTIC ANEMIA
JAMA: The Journal of the American Medical Association, 1952Since chloramphenicol is an efficient broad spectrum antibiotic that is widely used, the possibility that it may be the cause of hematological disorders is, naturally, a serious one. Recently, five cases of fatal aplastic anemia have come to our attention. In each instance, we believe chloramphenicol to be etiologically implicated. It is our purpose to
J J, RHEINGOLD, C L, SPURLING
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Oxyphenbutazone and aplastic anemia
The American Journal of Medicine, 1972Abstract Described here is a patient with rheumatoid arthritis in whom aplastic anemia developed while he was taking oxyphenbutazone. Although few cases of hematologic toxicity have been reported in association with this drug, the hazard is probably comparable to that with phenylbutazone.
R M, Pilewski +3 more
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Aplastic anemia: Pathophysiology
Seminars in Hematology, 2022Bone marrow failure (BMF) syndromes are a heterogeneous group of benign hematological conditions characterized by uni- or multi-lineage marrow and/or peripheral blood cytopenia(s), and can be classified in constitutional or acquired syndromes based on pathophysiology.
Giudice V., Selleri C.
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Aplastic and Hypoplastic Anemia
Pediatric Clinics of North America, 1980Aplastic anemia is an acquired or constitutional trilineage bone marrow failure with peripheral pancytopenia, evidence of cellular hypoplasia of marrow, and replacement of normal cellular elements by fat. In some cases the marrow may be hypoplastic and the peripheral cytopenia relatively mild.
J M, Lipton, D G, Nathan
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Erythropoietin in aplastic anemia
Blut, 1979The level of erythropoietin (Ep) was measured in sera and urine from aplastic anemia patients. Increased levels of Ep were demonstrated in sera from all 25 patients studied. An elevated level of Ep was found in the urine of 17 of 23 patients in whom the urine was tested. No correlation between blood hemoglobin and Ep level was observed.
V, Pavlovic-Kentera +4 more
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