Results 51 to 60 of about 66,503 (250)

Sublytic Terminal Complement Components Induce Eryptosis in Autoimmune Haemolytic Anaemia Related to IgM Autoantibodies [PDF]

, 2019
BACKGROUND/AIMS: Eryptosis, the suicidal death of red blood cells (RBCs), is characterized by phosphatidylserine (PS) exposure at the cell surface. It can be catalysed by a variety of abnormal conditions and diseases.
Balola, Abdelwahab Hassan Ahmed, Bartolmäs, Thilo, Mayer, Beate, Salama, Abdulgabar   +3 more
core   +1 more source

Characterisation of the Immunophenotype of Dogs with Primary Immune-Mediated Haemolytic Anaemia [PDF]

, 2016
Immune-mediated haemolytic anaemia (IMHA) is reported to be the most common autoimmune disease of dogs, resulting in significant morbidity and mortality in affected animals.
A Corato, A Doganci, A Knueppel, A Kojima, A Mqadmi, A Saxena, A Zanella, AL Rivas, AM Hall, AM Hall, B Sadlack, Barbara Glanemann, CA Lawson, CJ Elson, CJ Piek, CL Bennett, D Cao, D Pinheiro, DM Willerford, Douglas Thamm, E Ahmad, E Fagiolo, E Fagiolo, E Fagiolo, E Fagiolo, E von Elm, FJ Ward, G Kleiner, HF Titmarsh, James W. Swann, JH Buckner, JM Kim, JS Ellis, JW Swann, K Wing, KD Mitchell, Kelly Woods, KY King, L Han, L Llorente, L Llorente, L Xu, M Kjelgaard-Hansen, M Miyara, M Murai, MA Miller, ME Brunkow, NJ Davidson, NV Giltiay, OA Garden, Oliver A. Garden, P Pietschmann, PM McManus, RN Barker, RS Wildin, S Aggarwal, S Berentsen, S Lindley, S McCullough, S Sakaguchi, SA Bustin, SJ Ireland, V Viglietta, X Valencia, Ying Wu, Z Jiao   +65 more
core   +5 more sources

The Changing Landscape of Autoimmune Hemolytic Anemia

Frontiers in Immunology, 2020
Autoimmune hemolytic anemia (AIHA) is a greatly heterogeneous disease due to autoantibodies directed against erythrocytes, with or without complement activation.
W. Barcellini, B. Fattizzo
semanticscholar   +1 more source

Vitamin B12 and vitamin D deficiencies: An unusual cause of fever, severe hemolytic anemia and thrombocytopenia

Journal of Family Medicine and Primary Care, 2015
The array of diagnostic workup for pyrexia of unknown origin (PUO) generally revolves in searching for infections, inflammatory/autoimmune, and endocrine etiologies.
Vikas A Mishra, Rishit Harbada, Akhilesh Sharma   +2 more
doaj   +1 more source

Non-immune Hemolysis in Gaucher Disease and Review of the Literature Eliyakim Hershkop, Idan Bergman, Alina Kurolap, Najib Dally, and Hagit Baris Feld

Rambam Maimonides Medical Journal, 2021
Gaucher disease (GD) is an autosomal recessive disease characterized by the buildup of glucocerebrosides in macrophages, resulting in the formation of “Gaucher cells.” These cells predominantly infiltrate the liver, spleen, and bone marrow leading to ...
Eliyakim Hershkop, Idan Bergman, Alina Kurolap, Najib Dally, Hagit Baris Feldman   +4 more
doaj   +1 more source

Daratumumab monotherapy in refractory warm autoimmune hemolytic anemia and cold agglutinin disease

Blood Advances
Key Points • Daratumumab monotherapy may be an effective and well-tolerated treatment in more than half of patients with refractory AIHA and cold agglutinin disease.• Daratumumab can be effective on both the hemolysis and cold agglutinin–induced ...
M. Jalink, C. Jacobs, J. Khwaja, Dorothea Evers, Coty Y Bruggeman, B. Fattizzo, Marc Michel, Étienne Crickx, Quentin A A Hill, Ulrich Jaeger, A. Kater, Anja B U Mäkelburg, Anouk Breedijk, Peter te Boekhorst, Marlijn P A Hoeks, Masja de Haas, S. D'Sa, Josephine M I Vos   +17 more
semanticscholar   +1 more source

Severe refractory autoimmune hemolytic anemia with both warm and cold autoantibodies that responded completely to a single cycle of rituximab: a case report

Journal of Medical Case Reports, 2011
Introduction Mixed warm and cold autoimmune hemolytic anemia runs a chronic course with severe intermittent exacerbations. Therapeutic options for the treatment of hemolysis associated with autoimmune hemolytic anemia are limited.
Forte Frank, Gottesman Aaron, Varma Seema, Nakhl Fadi, Szerszen Anita, Gupta Shilpi, Dhar Meekoo   +6 more
doaj   +1 more source

Autoimmune hemolytic anemia: current knowledge and perspectives

Immunity & Ageing, 2020
Autoimmune hemolytic anemia (AIHA) is an acquired, heterogeneous group of diseases which includes warm AIHA, cold agglutinin disease (CAD), mixed AIHA, paroxysmal cold hemoglobinuria and atypical AIHA.
S. Michalak, A. Olewicz-Gawlik, Joanna Rupa-Matysek, E. Wolny-Rokicka, E. Nowakowska, L. Gil   +5 more
semanticscholar   +1 more source

Success of anti-CD20 monoclonal antibody treatment for severe autoimmune hemolytic anemia caused by warm-reactive immunoglobulin A, immunoglobulin G, and immunoglobulin M autoantibodies in a child: a case report

Journal of Medical Case Reports, 2017
Background Autoimmune hemolytic anemia is rare in children. First-line therapies for this disease consist of corticosteroids and intravenously administered immunoglobulin that are effective in most patients. However, a small proportion of cases (5 to 10%)
Houda Ajmi, Sameh Mabrouk, Saida Hassayoun, Haifa Regaieg, Minyar Tfifha, Chemli Jalel, Hadef Skouri, Noura Zouari, Saoussan Abroug   +8 more
doaj   +1 more source

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
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