Results 181 to 190 of about 87,700 (273)

Glucose‐6‐phosphate dehydrogenase deficiency is associated with improved survival in patients with acute myeloid leukemia treated with venetoclax and azacitidine

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency impairs cellular redox balance through reduced NADPH production and is the most common enzymatic disorder‐causing anemia. Venetoclax combined with azacitidine (Ven‐Aza) targets leukemic stem cells by disrupting oxidative phosphorylation and inducing mitochondrial stress. This study
Shira Buchrits   +7 more
wiley   +1 more source

Can We Really Believe This Platelet Count?

open access: yes
American Journal of Hematology, Volume 101, Issue 3, Page 566-567, March 2026.
James Manning   +3 more
wiley   +1 more source

Multisystem Complications in Postpartum-Onset Evans Syndrome: A Case Report. [PDF]

open access: yesCureus
Shazadeh Safavi K   +4 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao   +8 more
wiley   +1 more source

Mechanistic Consequences of Piezo1 Gain‐of‐Function Variants for Decreased Red Cell Survival in Hereditary Xerocytosis

open access: yes
American Journal of Hematology, Volume 101, Issue 3, Page 619-622, March 2026.
Asya Makhro   +11 more
wiley   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu   +4 more
wiley   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

open access: yesPediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak   +7 more
wiley   +1 more source

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