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Autoimmune Hemolytic Anemias

New England Journal of Medicine, 2021
Autoimmune Hemolytic Anemia Hemolytic anemias, which are rare, are often caused by autoimmune destruction of red cells. The hemolysis can be intravascular or extravascular.
Sigbjørn Berentsen, Wilma Barcellini
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Hemolytic Anemia with Hemoglobinuria

American Journal of Clinical Pathology, 1948
Hemolytic anemia with hemoglobinuria is frequently a striking clinical event indicative of extensive intravascular hemolysis. The condition lends itself to detailed study because of the morphologic abnormalities in the blood and bone marrow, the marked accumulation of hemoglobin and its derivatives in the blood plasma and urine, the aberrations of ...
D, STATS, L R, WASSERMAN, N, ROSENTHAL
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Congenital Hemolytic Anemia

Medical Clinics of North America, 2017
Red blood cell (RBC) destruction can be secondary to intrinsic disorders of the RBC or to extrinsic causes. In the congenital hemolytic anemias, intrinsic RBC enzyme, RBC membrane, and hemoglobin disorders result in hemolysis. The typical clinical presentation is a patient with pallor, anemia, jaundice, and often splenomegaly.
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Hemolytic Anemia in the Newborn

Clinics in Perinatology, 1995
Evaluation of hemolytic anemia in the newborn may be complicated owing to the physiologic changes that occur during this time; however, the newborn period is a time when congenital red cell abnormalities may first present and when maternal factors need to be considered.
A T, Matsunaga, B H, Lubin
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Cephalothin and Hemolytic Anemia

Annals of Internal Medicine, 1970
Excerpt To the editor: In the May 1970 issue of the ANNALS, Drs. Weinstein and Kaplan in the article "The Cephalosporins" made the following statement: "Therapy with cephalothin and, much less comm...
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Hydroxylamines and Hemolytic Anemia

1986
Hemolytic anemia, the uncompensated loss of red blood cells from the circulation, has been recognized as a side effect of drugs and other chemicals for over 50 years (Muelens, 1926; Cordes, 1926). This response is commonly associated with the aminoquinoline drugs, pamaquine and primaquine (Beutler, 1959); indeed the extensive studies carried out with ...
D J, Jollow   +2 more
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Autoimmune hemolytic anemia

The Indian Journal of Pediatrics, 2008
To study the clinico-hematological profile and treatment outcome in children suffering from auto immune hemolytic anemia (AIHA).Twelve children were diagnosed with auto immune hemolytic anemia over a period of four years. Direct antiglobulin test was positive in all the cases.
V, Gupta, J, Shukla, B D, Bhatia
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Autoimmune Hemolytic Anemia

Medical Clinics of North America, 2017
Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A, Liebman, Ilene C, Weitz
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Hemolytic Anemias in Pregnancy

Clinical Obstetrics and Gynecology, 1995
Polymorphism exists and complicates the diagnosis of inherited hemolytic anemias. However, with linkage DNA analysis and, on occasion, with characterization of the mutant gene, it is possible to make a diagnosis on the DNA level. This technique increases our understanding of the enzymatic defect and the relationship with clinical findings.
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Autoimmune Hemolytic Anemia

Pediatric Clinics of North America, 1980
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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