Results 261 to 270 of about 60,975 (302)
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Coagulation in the Pathophysiology of Hemolytic Anemias
Hematology American Society of Hematology Education Program, 2007AbstractCoagulation abnormalities are frequently reported in hemolytic anemias (HA). Several pathophysiologic mechanisms are common to different HA. In this review three different hemolytic disorders will be discussed.In sickle cell disease and in β-thalassemia, a thrombophilic status has been well documented as multifactorial involving hemostatic ...
Maria Domenica Cappellini +1 more
exaly +4 more sources
Archives of Internal Medicine, 1975
Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
openaire +2 more sources
Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Microangiopathic Hemolytic Anemia
New England Journal of Medicine, 1969IN 1917 Rous and Robertson1 suggested that fragmentation was the normal fate of the effete erythrocyte at the end of its life-span. More recently it has become recognized that erythrocytes may undergo fragmentation earlier if they are subjected to excessive trauma within the circulation.
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Tolbutamide-induced Hemolytic Anemia
Diabetes, 1977A 67-year-old female diabetic is presented who developed a Coombs'-positive hemolytic anemia after a year of treatment with tolbutamide. An IgG antibody was identified in the patient's serum that caused the agglutination of both the patient's red blood cells and tolbutamide-coated erythrocytes in the absence of complement. Such a reaction did not occur
P, Malacarne +3 more
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Human Pathology, 1983
Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
openaire +2 more sources
Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Hospital Practice, 1985
Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
openaire +2 more sources
Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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Current Opinion in Immunology, 1994
Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
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Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
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Postgraduate Medicine, 1978
The recognition, investigation, diagnosis, and treatment of hemolytic anemia are reviewed on the basis of a classification of the causes of hemolysis according to whether they are disorders of the membrane, hemoglobin, or metabolism of the erythrocyte; congenital or familial or acquired; and intrinsic or extrinsic.
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The recognition, investigation, diagnosis, and treatment of hemolytic anemia are reviewed on the basis of a classification of the causes of hemolysis according to whether they are disorders of the membrane, hemoglobin, or metabolism of the erythrocyte; congenital or familial or acquired; and intrinsic or extrinsic.
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Severe autoimmune hemolytic anemia; epidemiology, clinical management, outcomes and knowledge gaps
Frontiers in Immunology, 2023Dorothea Evers +2 more
exaly