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Medical Clinics of North America, 1980
Immune hemolytic anemia is an acquired anemia resulting from the premature destruction of red cells caused by the presence of antibody and/or complement on the red cell surface. The Coombs test, modified and improved, remains the mainstay of diagnosis.
Albert F. LoBuglio, John A. Axelson
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Immune hemolytic anemia is an acquired anemia resulting from the premature destruction of red cells caused by the presence of antibody and/or complement on the red cell surface. The Coombs test, modified and improved, remains the mainstay of diagnosis.
Albert F. LoBuglio, John A. Axelson
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Pediatric Clinics of North America, 1980
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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Warm Autoimmune Hemolytic Anemia.
New England Journal of Medicine, 2019Key Clinical Points Warm Autoimmune Hemolytic Anemia Warm autoimmune hemolytic anemia (WAHA) is a chronic, relapsing disease characterized by anemia, reticulocytosis, other laboratory evidence of h...
Robert A Brodsky
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Medical Clinics of North America, 2017
Red blood cell (RBC) destruction can be secondary to intrinsic disorders of the RBC or to extrinsic causes. In the congenital hemolytic anemias, intrinsic RBC enzyme, RBC membrane, and hemoglobin disorders result in hemolysis. The typical clinical presentation is a patient with pallor, anemia, jaundice, and often splenomegaly.
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Red blood cell (RBC) destruction can be secondary to intrinsic disorders of the RBC or to extrinsic causes. In the congenital hemolytic anemias, intrinsic RBC enzyme, RBC membrane, and hemoglobin disorders result in hemolysis. The typical clinical presentation is a patient with pallor, anemia, jaundice, and often splenomegaly.
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European Journal of Haematology, 2018
Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies.
Georges E. Tanios +2 more
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Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies.
Georges E. Tanios +2 more
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The Indian Journal of Pediatrics, 2008
To study the clinico-hematological profile and treatment outcome in children suffering from auto immune hemolytic anemia (AIHA).Twelve children were diagnosed with auto immune hemolytic anemia over a period of four years. Direct antiglobulin test was positive in all the cases.
B. D. Bhatia +2 more
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To study the clinico-hematological profile and treatment outcome in children suffering from auto immune hemolytic anemia (AIHA).Twelve children were diagnosed with auto immune hemolytic anemia over a period of four years. Direct antiglobulin test was positive in all the cases.
B. D. Bhatia +2 more
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Hemolytic Anemias in Pregnancy
Clinical Obstetrics and Gynecology, 1995Polymorphism exists and complicates the diagnosis of inherited hemolytic anemias. However, with linkage DNA analysis and, on occasion, with characterization of the mutant gene, it is possible to make a diagnosis on the DNA level. This technique increases our understanding of the enzymatic defect and the relationship with clinical findings.
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Medical Clinics of North America, 2017
Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A. Liebman, Ilene C. Weitz
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Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A. Liebman, Ilene C. Weitz
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Hydroxylamines and Hemolytic Anemia [PDF]
, 1986 Hemolytic anemia, the uncompensated loss of red blood cells from the circulation, has been recognized as a side effect of drugs and other chemicals for over 50 years (Muelens, 1926; Cordes, 1926). This response is commonly associated with the aminoquinoline drugs, pamaquine and primaquine (Beutler, 1959); indeed the extensive studies carried out with ...
James H. Harrison +2 more
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Seminars in hematology (Print), 2018
The classical complement pathway and, to some extent, the terminal pathway, are involved in the immune pathogenesis of autoimmune hemolytic anemia (AIHA).
S. Berentsen
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The classical complement pathway and, to some extent, the terminal pathway, are involved in the immune pathogenesis of autoimmune hemolytic anemia (AIHA).
S. Berentsen
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