Results 161 to 170 of about 68,346 (260)

Impact of Upper Gastrointestinal Involvement on Clinical Outcomes in Paediatric Inflammatory Bowel Disease

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to assess the clinical implications of upper gastrointestinal (UGI) involvement in paediatric inflammatory bowel disease (IBD). Methods This retrospective cohort study included children diagnosed with IBD between 2010 and 2023, who underwent a UGI endoscopic evaluation at diagnosis and were followed for at least ...
Ofek Aloni   +8 more
wiley   +1 more source

Screen‐Detected Coeliac Disease in a Nationally Representative Cohort: Health Indicators, Long‐Term Outcomes and Mortality

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a nationally representative Finnish cohort, screen‐detected coeliac disease was associated with iron deficiency, anaemia, and an atherogenic lipid profile at diagnosis, but long‐term gluten‐free treatment did not adversely affect quality of life, metabolic health, or mortality; supporting a favourable benefit‐harm balance for population‐based ...
Iida Ahonen   +5 more
wiley   +1 more source

Bilateral Supracondylar Process in a Subadult in the Late Antique Age: A Case Report

open access: yesArchaeometry, EarlyView.
ABSTRACT During the excavation procedures for the railway trait Napoli‐Cancello, in the city of Afragola (Naples), several burials dating back to the Late Antique Age were found. One of them was an amphora burial (enchytrismòs) and contained the skeletal remains of a subadult individual affected by bilateral supracondylar process. Supracondylar process
Barbara Albanese   +3 more
wiley   +1 more source

Perioperative Anemia, Transfusion Practices, and Patient Blood Management: Lessons from the COVID-19 Pandemic. [PDF]

open access: yesHematol Rep
Ionescu A   +6 more
europepmc   +1 more source

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

open access: yesBritish Journal of Haematology, EarlyView.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

open access: yesBritish Journal of Haematology, EarlyView.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo   +3 more
wiley   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy