Results 181 to 190 of about 1,398,221 (253)

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

British Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi, Nandakumar Natarajan, Kathryn E. Dickerson, Richard A. Voit   +3 more
wiley   +1 more source

Iron, Tuberculosis, and Particle-Related Exposures Including Smoking. [PDF]

Pathogens
Ghio AJ, Pennington ER, Pulczinski JC, Hilborn ED, Tilley SL.   +4 more
europepmc   +1 more source

Iron Supplementation and Neurodevelopmental Outcomes in Infancy and Early Childhood: A Review. [PDF]

Children (Basel)
Fitz SJT, Sanchez VJ, Hoyos AM, Pena DEM.   +3 more
europepmc   +1 more source

Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia

British Journal of Haematology, EarlyView.
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet, Priscilla Boizeau, Zinedine Haouari, Berengère Koehl, Monique Elmaleh, Emmanuelle Lesprit, Florence Missud, Ghislaine Ithier, Laurent Holvoet, Valentine Brousse, Christophe Delclaux, André Denjean, Suzanne Verlhac, Corinne Alberti, André Baruchel, Nathalie Couque, Malika Benkerrou   +16 more
wiley   +1 more source

A Narrative Review of Zinc Deficiency-Associated Anemia. [PDF]

Hematol Rep
Basmajian K, Dermarderosian A, Thoreson RJ, Adams J, Farjami C, Yang A, Akhtari E, Araji S, Khan Z, Saadat S, Arabian S, Tansy C, Knutzen G, Akhtari M.   +13 more
europepmc   +1 more source

Functional assessment of inherited myeloid neoplasm‐associated SAMD9L germline variants via Monoallelic CRISPR modelling

British Journal of Haematology, EarlyView.
Summary While the majority of myeloid neoplasms are sporadic, the increasing application of germline genetic testing has led the World Health Organization to designate ‘Myeloid malignancies with germline predisposition’ as a distinct clinical entity, carrying major implications for clinical care and research.
Elena Vuelta, Alessandro Liquori, Matias Morín, Lucia Soletto, Miguel Ángel Marugal, Marta Santiago‐Balsera, Miguel Gallardo, Miguel Ángel Moreno‐Pelayo, José Cervera, Alejandra Sanjuan‐Pla   +9 more
wiley   +1 more source

Obesity and Iron Metabolism: Mechanisms, Status Assessment, and Clinical Implications. [PDF]

Curr Obes Rep
Aguree S, Meng X.
europepmc   +1 more source

Iron, ESA, and HIF-Inhibitors: Are There Other Opportunities to Improve Anemia of CKD? [PDF]

J Clin Med
Bonomini M, Vecchio LD, Minutolo R, Sirolli V, Locatelli F.   +4 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Perioperative Anemia Investigation and Management in Vascular Surgery: A Single-Center Retrospective Service Evaluation. [PDF]

Cureus
Ali HH, Pillay W.
europepmc   +1 more source