Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Effects of Immunoadsorption on Markers of Iron Metabolism: A Case Series. [PDF]
Ginthör NE +10 more
europepmc +1 more source
Anemia, Iron Deficiency, and Iron Supplementation in Relation to Mortality among HIV-Infected Patients Receiving Highly Active Antiretroviral Therapy in Tanzania. [PDF]
Haider BA +9 more
europepmc +1 more source
Whole‐genome sequencing of ~50,000 individuals from the Tohoku Medical Megabank (TMM) cohort defines the prevalence, mutational landscape, and age dependency of clonal hematopoiesis in the Japanese population, demonstrating overall concordance with clonal hematopoiesis detected in cancer patients.
SungGi Chi +12 more
wiley +1 more source
Improving Iron Status Without Iron: Clinical Insights From Recombinant Human Lactoferrin Supplementation. [PDF]
Evans C, Peterson R, Antonio J, Clark A.
europepmc +1 more source
S3 guideline diagnostics and therapy of alopecia areata – Part 1: Diagnostics and epidemiology
Summary In the project funded by the Innovation Committee at the G‐BA, the S3 guideline for the diagnosis and treatment of AA was developed between 2023 and 2025. The interdisciplinary expert panel consisted of representatives from the German Dermatological Society, in particular from the Pediatric Dermatology Working Group, the Professional ...
Ulrike Blume‐Peytavi +13 more
wiley +1 more source
There are sex‐specific disparities in the prevalence of different isolated intermediate hyperglycaemic states, which, in the context of clinical guidance to use FPG or HbA1c for identification, may contribute to underdiagnosis and undertreatment in primary care and introduce ascertainment bias into research and policy. Abstract Aims To evaluate the sex‐
Louise Cooper +4 more
wiley +1 more source
Prevalence and Determinants of Anemia and Iron Deficiency Anemia Among Patients With Diabetes Mellitus in Cameroon: An Analytical Cross-Sectional Study. [PDF]
Tedong L +7 more
europepmc +1 more source
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
A Child With Iron-Refractory Iron Deficiency Anemia: A Rare Case Associated With Hiatal Hernia. [PDF]
Ketema W +11 more
europepmc +1 more source

