Diagnosis and treatment of macrocytic anemias in adults [PDF]
Anemia is one of the most common health problems in the primary care setting. Macrocytosis in adults is defined as a red blood cell (RBC) mean corpuscular volume (MCV) >100 femtoliter (fL).
Hirokawa Makoto, Nagao Takayo
exaly +6 more sources
Unveiling VEXAS Syndrome: When Skin Manifestations and Monoclonal Gammopathy Precede Myeloid-Lineage Hematologic Abnormality. [PDF]
VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome is a rare disorder caused by somatic UBA1 gene mutations, characterized by autoinflammation and hematologic abnormalities, particularly affecting myeloid‐lineage progenitors. Sensitive markers include macrocytic anemia, vacuolization of bone marrow precursors, and myelodysplasia.
Di Centa L+4 more
europepmc +2 more sources
Etiology and Pathogenesis of Macrocytic Anemia [PDF]
Anemia is the most common conditions detected by primary care doctors in Indonesia and worldwide. In 2010, the global prevalence of anemia was 32.9%; that is, more than 2.2 billion people have anemia in the world.
Gede Andhika, I Komang
exaly +2 more sources
Prevalence of potential underlying aetiology of macrocytic anaemia in Dutch general practice [PDF]
Background: Macrocytic anaemia (MCV \xe2\x89\xa5 100 fL) is a relatively common finding in general practice. However, literature on the prevalence of the different causes in this population is limited.
Rob Castel+2 more
exaly +4 more sources
The maturation of reticulocytes. II. Life-span of red cells originating from stress reticulocytes [PDF]
Life-spans of macroreticuloytes and macrocytic red cells were studied. Rabbits were made anemic by injecting phenylhydrazine. Peripheral blood rich in reticulocytes was drawn, labeled with 3H-amino acids, and injected back into the anemic animal ...
Shimada, Atsuko
core +1 more source
Efficacy of RBC histogram in the diagnosis of morphological types of anaemia compared with peripheral smear [PDF]
Background: Anaemia constitutes an important diagnostic and clinical category of haematological disorders. Along with peripheral smear histogram is used to interpret the abnormal RBC morphology.
P. L., Jayalakshmy+2 more
core +2 more sources
Studies on erythropoiesis II. In vitro studies on red cell proliferation under varied oxygen tension [PDF]
For the purpose to reveal the mechanism of the stimulated erythropoiesis in anemic condition, the author observed the numerical changes of the erythroblasts from normal rabbit bone marrow cultured under the environment of varied oxygen tensions, and ...
Shibata, Takashi
core +1 more source
Thyroid dysfunction and anaemia in a large population-based study. [PDF]
OBJECTIVE AND BACKGROUND: Anaemia and thyroid dysfunction are common and often co-occur. Current guidelines recommend the assessment of thyroid function in the work-up of anaemia, although evidence on this association is scarce.
Angelillo-Scherrer, A.+10 more
core +3 more sources
Markers of inflammation and mortality in a cohort of patients with alcohol dependence [PDF]
.Inflammation and intestinal permeability are believed to be paramount features in the development of alcohol-related liver damage. We aimed to assess the impact of 3 surrogate markers of inflammation (anemia, fibrinogen, and ferritin levels) on mid-term
Bolao, Ferran+7 more
core +2 more sources
Change in hematologic indices over time in pediatric inflammatory bowel disease treated with azathioprine [PDF]
Azathioprine leads to changes in mean corpuscular volume (MCV) and white blood cell (WBC) indices reflecting efficacy or toxicity. Understanding the interactions between bone marrow stem cells and azathioprine could highlight abnormal response patterns ...
A Timmer+18 more
core +2 more sources