Results 21 to 30 of about 7,347 (182)

Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital

Journal of Family Medicine and Primary Care, 2019
Background: The prevalence of anemia increases with age. Some serious underlying conditions may lead to anemia in the old age. The present study was undertaken to detect and do morphological typing of anemia and further delineate etiological factors in ...
Nitin Raisinghani, Sunil Kumar, Sourya Acharya, Aditi Gadegone, Vinay Pai   +4 more
doaj   +1 more source

Therapeutic Outcomes in VEXAS Syndrome: A Multicenter Comparative Cohort of Allogeneic Hematopoietic Stem Cell Transplantation and Hypomethylating Agents

American Journal of Hematology, EarlyView.
ABSTRACT Hypomethylating agents (HMA) and allogeneic hematopoietic stem cell transplantation (alloHSCT) have both demonstrated remissions in VEXAS; however, comparative data is lacking. We conducted a multicenter, retrospective analysis of 66 patients diagnosed with VEXAS syndrome treated with HMA (n = 35) or alloHSCT (n = 31). Baseline characteristics
Saubia Fathima, Margaret Mei‐Kay Wong, Jesus Gonzalez‐Lugo, Susan M. Geyer, Ali Alsugair, Maria Sirenko, Kimberly J. Langer, Terra L. Lasho, Christy Finke, Jun Choi, Maher Abdul‐Hay, Gary Ho, Mark R. Litzow, Aasiya Matin, Urshila Durani, Mehrdad Hefazi, William J. Hogan, Mithun V. Shah, Aref Al‐Kali, Kebede H. Begna, Naseema Gangat, Antoine N. Saliba, Ronald S. Go, Tariq Kewan, Gabriel Bartoo, Jade Kutzke, Kristen McCullough, Kenneth J. Warrington, Megan Sullivan, Kaaren K. Reichard, Horatiu Olteanu, Hemant Murthy, Talha Badar, Yael Kusne, Jeanne Palmer, Saurabh Chhabra, Nathan Punwani, Mary Riwes, Joseph P. McGuirk, Elizabeth F. Krakow, Amelia Langston, Taxiarchis Kourelis, David Dingli, James Foran, Matthew J. Koster, Mrinal M. Patnaik, David B. Beck, Hassan B. Alkhateeb, Abhishek A. Mangaonkar   +48 more
wiley   +1 more source

Evaluation of mean corpuscular volume among anemic people with HIV in North America following ART initiation

AIDS Research and Therapy
Background Anemia is common and associated with increased morbidity among people with HIV (PWH). Classification of anemia using the mean corpuscular volume (MCV) can help investigate the underlying causative factors of anemia.
Raynell Lang, Sally B. Coburn, M. John Gill, Amy C. Justice, Jennifer Grossman, Kelly A. Gebo, Michael A. Horberg, Angel M. Mayor, Michael J. Silverberg, Kathleen A. McGinnis, Brenna Hogan, Richard D. Moore, Keri N. Althoff, for the North American AIDS Cohort Collaboration on Research, Design (NA-ACCORD) of the International Epidemiologic Databases to Evaluate AIDS (IeDEA)   +13 more
doaj   +1 more source

Folic Acid-Induced Fall in Phenytoin Levels and Seizure Recurrence

Pediatric Neurology Briefs, 2005
Recurrence of seizures is reported in an adult after addition of folic acid for treatment of a macrocytic anemia.
J Gordon Millichap
doaj   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Lipid Interference Flagging and Haemoglobin Correction in Lipemic Samples With a Hematology Analyzer

Journal of Clinical Laboratory Analysis, EarlyView.
A flagging method was developed based on the changes of routine blood parameters and blood cell scattergram. It highlights the clinical value of the “Lipid Particles?” flag in effectively identifying lipid interference. This study supports the use of HGB‐O measured by ERP channel as a robust tool for improving diagnostic accuracy in lipid interference ...
Yinhua Fan, Yimin Shen, Dongmei Liu, Yong Wang, Jun Cao, Bo Zhao, Yushuai Ma, Zijie Chen, Shuaishuai Zhang   +8 more
wiley   +1 more source

A Proposed Clinical Diagnostic Framework for Short Telomere Syndrome

Clinical Genetics, EarlyView.
We propose a phenotype‐based diagnostic framework for short telomere syndrome that integrates age‐adjusted telomere length, phenotypic manifestations, and genetic findings, where available. The framework is intended to guide clinical evaluation, longitudinal surveillance, and individualized management while acknowledging limitations in current telomere
Andrew Courtwright, Richard A. King, Jennie Vagher, Cate T. Levy, Juan Gallegos F. Orozco, Luis FZ Batista, Afaf Osman, Srinivas Tantavahi, Mary Beth Scholand   +8 more
wiley   +1 more source

Double Robertsonian translocations in an infertile patient with macrocytic anemia: a case report

Molecular Cytogenetics, 2020
Background Constitutional heterologous double Robertsonian translocations (DRT) between chromosomes 13/14 and chromosomes 14/15 with 44 chromosomes are extremely rare.
Ramakrishnan Sasi, Jamie Senft, Michelle Spruill, Soham Rej, Peter L. Perrotta   +4 more
doaj   +1 more source

A study on metformin-induced anemia using red blood cell indices and red cell distribution width

Assam Journal of Internal Medicine, 2023
Background: Diabetic patients on metformin may have increased risk of developing anemia. Hematological parameters can easily reflect anisocytosis and differential analysis of anemia.
Sasank Lingam, Himavathy Kodandarao Gara, Dharma Rao Vanamali   +2 more
doaj   +1 more source

A quantitative dissection of the DNA‐binding properties of pathogenic GATA1 mutants

The FEBS Journal, EarlyView.
Transcription factor activity is influenced by cell context, accessibility of target sequences, and co‐factor recruitment. Quantitatively characterizing the consequences of individual mutations in the transcription factors or their target sequences remains technically challenging. Zambo et al. use mutant GATA1‐ATP2B4 binding to illustrate an innovation
Kaoru Takasaki
wiley   +1 more source