Severe Macrocytic Anemia Associated With a Novel ALAS2 Mutation: A Case Report and Literature Review [PDF]
Clinical Case ReportsX‐linked sideroblastic anemia (XLSA), caused by pathogenic variants in ALAS2, typically presents as microcytic anemia in males. However, heterozygous females occasionally exhibit an atypical macrocytic phenotype, often leading to diagnostic ambiguity and
Haodong Cai +5 more
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Diagnosis and treatment of macrocytic anemia in a perinatal common marmoset: a case report [PDF]
Laboratory Animal Research, 2022 Background The common marmoset is widely used in current biomedical research for various research fields. We observed macrocytic anemia in a perinatal common marmoset with gradual weight loss and diarrhea. The objective of this case report is to describe
Jong-Min Kim +4 more
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Case Reports in Hematology, 2022 Splenomegaly is manifested by a variety of etiologies, one of which is macrocytic anemia. Macrocytic anemia has multiple causes in itself that include; folate (Vitamin B9) and Cobalamin (vitamin B12) deficiencies.
Alexis Lordi +3 more
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Peripheral Blood Smear and RBC Histogram in Anemia: A Two-Year Observational Study [PDF]
Saintika Medika, 2023 In our geographic region, anemia is a prevalent medical condition, and our study focuses on the use of comprehensive hematological parameters, including the RBC Histogram and peripheral blood smears, as an initial diagnostic approach to promptly identify
Harshul Patidar +3 more
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Double Heterozygous CDAN1 Variants of Uncertain Significance Associated With a Phenotype Consistent With Congenital Dyserythropoietic Anemia Type 1 [PDF]
Case Reports in HematologyCongenital dyserythropoietic anemia is a group of hereditary disorders characterized by erythroid hyperplasia and ineffective erythropoiesis, resulting in anemia of varying severity.
Kevin G. Zablonski +3 more
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MicroRNA Dysregulation and Hepatic Involvement in Alcohol-Related Macrocytic Anaemia: Links to Severity Without Predictive Value for Treatment Response [PDF]
LifeBackground: Alcohol-related macrocytic anemia remains insufficiently characterized, particularly regarding molecular correlates of disease severity and treatment response.
Corina Porr +5 more
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C-reactive protein-triglyceride-glucose index (CTI) as a predictor of chronic liver disease in adults with macrocytic anemia [PDF]
Scientific ReportsMacrocytic anemia is frequently associated with liver dysfunction; however, reliable biomarkers for predicting chronic liver disease (CLD) in this population remain limited. This longitudinal study included 693 individuals with macrocytic anemia from the
Wenjing Shang +4 more
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Beyond Hemoglobin Levels: Integrating Anemia Phenotyping Into Prognostic Models for Patients With Stroke Following Intravenous Thrombolysis [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Anemia predicts poor outcomes after intravenous thrombolysis in acute ischemic stroke. Whether morphological anemia subtypes differentially affect prognosis remains unclear.
Senwei Tan +11 more
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Elevated Serum Lipopolysaccharides and Intrinsic Factor Autoantibodies Correlate With Macrocytic Anemia Among People With HIV [PDF]
Immunity, Inflammation and DiseaseIntroduction Human immunodeficiency virus (HIV) infection is associated with various comorbidities, including macrocytic anemia, though the role of the infection is unclear. HIV has been implicated in microbial translocation and altered immune responses.
Daniel Amakye +6 more
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Frontiers in Pharmacology, 2021 Background: Mean corpuscular volume (MCV) is major used as an indicator for the differential diagnosis of anemia. Macrocytic anemia in decompensated cirrhosis is common.
Tian-Yu Zhao +4 more
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