Genome-wide association study identifies five risk loci for pernicious anemia
Nature Communications, 2021 Pernicious anemia shows co-incidence with autoimmune disorders, yet the genetic basis for this condition is understudied. Here, the authors perform a genome-wide association study meta-analysis on pernicious anemia, identifying five susceptibility loci ...
Triin Laisk-Podar +2 more
exaly +2 more sources
Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness—a case report [PDF]
Journal of Medical Case ReportsBackground Pernicious anemia, also called Biemer’s disease, is an autoimmune disease and the most common cause of cobalamin deficiency globally. Various genetic, environmental, and immunological factors interplay to lead to its presentation.
Venance Emmanuel Mswelo +8 more
doaj +2 more sources
A long-standing undiagnosed case of vitamin B12 deficiency: a case report [PDF]
Journal of Medical Case ReportsBackground Pernicious anemia, an autoimmune disease, presents with gradual, nonspecific symptoms, often leading to delayed diagnosis owing to its overlap with other conditions and variability in laboratory findings, such as neurological symptoms without ...
Amirhossein Mesgarankarimi +2 more
doaj +2 more sources
Is Cholesterol Sulfate Deficiency a Common Factor in Preeclampsia, Autism, and Pernicious Anemia? [PDF]
Entropy, 2012 In a recent paper, we proposed that a contributing factor in autism is a deficiency in cholesterol sulfate supply. In this paper, we investigate a link between preeclampsia and subsequent autism in the child, and we hypothesize that both conditions can ...
Jingjing Liu +2 more
doaj +6 more sources
A case of asymptomatic pancytopenia with clinical features of hemolysis as a presentation of pernicious anemia [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2016 Pernicious anemia is an autoimmune disease with a variety of clinical presentations. We describe a case of pernicious anemia presenting with pancytopenia with hemolytic features.
Venkateswara K. Kollipara +3 more
doaj +1 more source
Pernicious Anemia in an Adult with Trisomy 21
Case Reports in Immunology, 2023 Pernicious anemia is an autoimmune disease caused by the malabsorption of vitamin B12. It usually appears in the elderly. People with trisomy 21 are susceptible to autoimmune diseases. This susceptibility is thought to be due to altered expression of the
Kentaro Kamada +4 more
doaj +1 more source
Type-1 Grade 2 Multi-Focal Gastric Neuroendocrine Tumors Secondary to Chronic Autoimmune Gastritis
Frontiers in Medicine, 2022 BackgroundChronic autoimmune gastritis (CAG) refers to chronic atrophic gastritis due to autoimmunity. Loss of gastric glands in CAG results in hypergastrinemia and achlorhydria leading to Vitamin B12 deficiency and hyperplasia of G cells and ...
Ziqi Yu +4 more
doaj +1 more source
MCPIP1 deficiency in mice results in severe anemia related to autoimmune mechanisms. [PDF]
PLoS ONE, 2013 Autoimmune gastritis is an organ-specific autoimmune disease of the stomach associated with pernicious anemia. The previous work from us and other groups identified MCPIP1 as an essential factor controlling inflammation and immune homeostasis. MCPIP1(-/-)
Zhou Zhou +9 more
doaj +1 more source
Vitiligo and autoimmune thyroid disorders [PDF]
, 2017 Vitiligo represents the most common cause of acquired skin, hair and oral depigmentation, affecting 0.5-1% of the population worldwide. It is clinically characterized by the appearance of disfiguring circumscribed skin macules following melanocyte ...
Baldini, Enke +10 more
core +6 more sources
F1000Research, 2020 Primary gastric cancer remains one of the most prevalent malignancies worldwide. Often patients remain asymptomatic until it is detected at an advanced stage with a poor prognosis.
Syed Kamran +5 more
doaj +1 more source