Results 21 to 30 of about 313,805 (193)

Autoimmune gastritis, with or without pernicious anemia: epidemiology, risk factors, and clinical management

Therapeutic Advances in Gastroenterology, 2021
Autoimmune gastritis (AIG) is a chronic immune-mediated, inflammatory condition that involves the destruction of the gastric oxyntic mucosa through the autoimmune-mediated loss of parietal cells, with replacement by atrophic and metaplastic tissue ...
S. Rustgi, Priyesha Bijlani, Shailja C. Shah   +2 more
semanticscholar   +1 more source

Pernicious Anemia in an Adult with Trisomy 21

Case Reports in Immunology, 2023
Pernicious anemia is an autoimmune disease caused by the malabsorption of vitamin B12. It usually appears in the elderly. People with trisomy 21 are susceptible to autoimmune diseases. This susceptibility is thought to be due to altered expression of the
Kentaro Kamada, Osamu Kawano, Satoshi Yakuwa, Kentaro Wakasa, Kimiaki Uetake   +4 more
doaj   +1 more source

Genome-wide association study identifies five risk loci for pernicious anemia

Nature Communications, 2021
Pernicious anemia shows co-incidence with autoimmune disorders, yet the genetic basis for this condition is understudied. Here, the authors perform a genome-wide association study meta-analysis on pernicious anemia, identifying five susceptibility loci ...
Triin Laisk, Maarja Lepamets, Mariann Koel, Erik Abner, Estonian Biobank Research Team, Reedik Mägi   +5 more
doaj   +1 more source

Type-1 Grade 2 Multi-Focal Gastric Neuroendocrine Tumors Secondary to Chronic Autoimmune Gastritis

Frontiers in Medicine, 2022
BackgroundChronic autoimmune gastritis (CAG) refers to chronic atrophic gastritis due to autoimmunity. Loss of gastric glands in CAG results in hypergastrinemia and achlorhydria leading to Vitamin B12 deficiency and hyperplasia of G cells and ...
Ziqi Yu, Aiyao Wang, Chong Hu, Tao Yu, Jianyong Chen   +4 more
doaj   +1 more source

MCPIP1 deficiency in mice results in severe anemia related to autoimmune mechanisms. [PDF]

PLoS ONE, 2013
Autoimmune gastritis is an organ-specific autoimmune disease of the stomach associated with pernicious anemia. The previous work from us and other groups identified MCPIP1 as an essential factor controlling inflammation and immune homeostasis. MCPIP1(-/-)
Zhou Zhou, Ruidong Miao, Shengping Huang, Brandon Elder, Tim Quinn, Christopher J Papasian, Jifeng Zhang, Daping Fan, Y Eugene Chen, Mingui Fu   +9 more
doaj   +1 more source

Pernicious Anemia

Definitions, 2020
Copyright 2009, American Society for Investigative Pathology 32 In 1855, Thomas Addison at Guy's Hospital described a lethal, idiopathic anemia that in 1872 was given the name pernicious anemia by Biemer.
R. B. Farnsworth
semanticscholar   +1 more source

Case Report: Simultaneously diagnosed gastric adenocarcinoma and pernicious anemia – a classic association [version 1; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2020
Primary gastric cancer remains one of the most prevalent malignancies worldwide. Often patients remain asymptomatic until it is detected at an advanced stage with a poor prognosis.
Syed Kamran, Mattias K. Dilling, Nathaniel A. Parker, Joel Alderson, Nathan D. Tofteland, Quoc V. Truong   +5 more
doaj   +1 more source

Pernicious anemia with unusual associations

Iraqi Journal of Hematology, 2022
Pernicious anemia (PA) is an autoimmune disease due to vitamin B12 deficiency secondary to Intrinsic Factor deficiency. A 65-year-old man presented with left lower limb swelling and pain for one week.
C A Mansoor
doaj   +1 more source

Coexistence of Pernicious Anemia and Myasthenia Gravis—A Rare Combination of Autoimmune Diseases in Taiwan

Journal of the Formosan Medical Association, 2006
About 5-10% of patients with myasthenia gravis concomitantly have other autoimmune diseases. However, the coexistence of myasthenia gravis and pernicious anemia is rare.
Kuo-Hsuan Chang, Rong-Kuo Lyu, Long-Sun Ro, Yih-Ru Wu, Chiung-Mei Chen   +4 more
doaj   +1 more source

Case Report: Simultaneously diagnosed gastric adenocarcinoma and pernicious anemia – a classic association [version 2; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2020
Primary gastric cancer remains one of the most prevalent malignancies worldwide. Often patients remain asymptomatic until it is detected at an advanced stage with a poor prognosis.
Syed Kamran, Mattias K. Dilling, Nathaniel A. Parker, Joel Alderson, Nathan D. Tofteland, Quoc V. Truong   +5 more
doaj   +1 more source