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THE ADOLESCENT WITH SICKLE CELL ANEMIA
Hematology/Oncology Clinics of North America, 1996Adolescence is a time of intense change and turmoil. Helping patients with sickle cell disease have a smooth transition from the pediatric to adult health care environment is an important and meaningful experience. Facilitating the patient's transition, however, takes time and effort.
T R, Kinney, R E, Ware
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Cholestasis in sickle cell anemia
The American Journal of Medicine, 1964Abstract A patient with sickle cell anemia who presented with marked cholestatic jaundice is described, with emphasis upon the difficulties encountered in differentiating this symptom complex from extrahepatic obstruction due to stone formation. This patient had extraordinarily high serum bilirubin levels, apparently the result of increased bilirubin ...
F M, KLION, M J, WEINER, F, SCHAFFNER
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PATHOPHYSIOLOGY OF SICKLE CELL ANEMIA
Hematology/Oncology Clinics of North America, 1996The anemia results from the markedly shortened circulatory survival of SS cells, together with a limited erythropoietic response. Both independent properties of Hb S-polymerization of the deoxy-Hb and instability of the oxy-Hb-contribute to early red cell destruction by effects on the Hb and on the red cell membranes.
R M, Bookchin, V L, Lew
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Archives of Pediatrics & Adolescent Medicine, 1958
Sickling can be produced in the blood of young Negro babies with sickle-cell trait. The percentage of cells showing this change is low but will increase as the infant matures. The homozygous state is present from birth; however, recognition of the symptomatic condition is rare in infants under the age of 4 months.
S L, LEIKIN, J W, McCOO
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Sickling can be produced in the blood of young Negro babies with sickle-cell trait. The percentage of cells showing this change is low but will increase as the infant matures. The homozygous state is present from birth; however, recognition of the symptomatic condition is rare in infants under the age of 4 months.
S L, LEIKIN, J W, McCOO
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The electrocardiogram in sickle-cell anemia
American Heart Journal, 1955Abstract 1. 1. Sixty random patients with a hematologic diagnosis of sickle-cell anemia have been studied for clinical and electrocardiographic evidence of heart disease. 2. 2. The various types of electrocardiographic abnormalities have been discussed and compared with those found in the literature.
C L, LINDO, L R, DOCTOR
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Hypersplenism in Sickle Cell Anemia
Archives of Internal Medicine, 1964Although splenomegaly in children with sickle cell anemia is common, massive enlargement associated with thrombocytopenia and very severe anemia is rare. In such patients, splenectomy has been followed by increase in platelet count and hemoglobin concentration. This suggests that an acquired hypersplenism aggravated the hemolytic process.
E C, ROSSI +3 more
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The Treatment of Sickle Cell Anemia
Archives of Internal Medicine, 1974"Sickle cell crisis" is a diagnosis made by exclusion, and infection must be ruled out as a cause of symptoms whenever a patient becomes acutely ill. Partial exchange transfusion is an important therapeutic tool, for it seems to interrupt "the vicious cycle of sickling" in some instances and forestall it in others.
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Sickle Cell Anemia and Pregnancy
Postgraduate Medicine, 1952A study was made of 18 cases of sickle cell anemia, 4 of which were complicated by pregnancy. These 4 cases are reported in detail, including the postmortem findings for one of them. The frequency of the various symptoms of sickle cell anemia and a summary of the cases complicated by pregnancy are presented in tabulated form.
R, CHARET, R, WALTMAN, H, FERNBACH
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Depression and Sickle Cell Anemia
Southern Medical Journal, 1981Very few reports of depression occurring with sickle cell anemia have been documented. We have reported three cases of depression in patients with sickle cell anemia that were referred over a relatively brief period, and that were successfully treated with antidepressant medication and family therapy.
C, Morin, E M, Waring
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The Inheritance of Sickle Cell Anemia
Science, 1949IF A DROP OF BLOOD is collected from each member of a randomly assembled series of American Negroes and sealed under a cover slip with vaseline, to be observed at intervals up to 72 hours, in the case of about 8 percent of the individuals composing the series a high proportion of the erythrocytes will be observed to assume various bizarre oat, sickle ...
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