Results 41 to 50 of about 298,625 (226)

Differential diagnosis of iron deficiency [PDF]

, 2010
Iron deficiency is considered to be the commonest hematological pathology in humans. Thus, the essential steps in an adequate approach of iron deficiency include: the proper identification of its causes and the differentiation between iron deficiency and
Figueiredo, Maria Stella, Vicari, Perla
core   +1 more source

Ring sideroblasts and sideroblastic anemias

Haematologica, 2011
The sideroblastic anemias are a heterogeneous group of inherited and acquired disorders characterized by anemia of varying severity and the presence of ring sideroblasts in the bone marrow ...
CAZZOLA, MARIO, INVERNIZZI, ROSANGELA
openaire   +3 more sources

Transient Sideroblastic Anemia Post-COVID-19 Infection

Cureus, 2022
A 57-year-old gentleman presented to the hospital with progressive fatigue and dyspnea on exertion three months after recovering from COVID-19. He was noted to have severe anemia with reticulocytopenia.
N. Mukhi, Luis R Soto, Aparna Vuppala
semanticscholar   +1 more source

Iron–sulfur clusters: from metals through mitochondria biogenesis to disease [PDF]

, 2018
Iron–sulfur clusters are ubiquitous inorganic co-factors that contribute to a wide range of cell pathways including the maintenance of DNA integrity, regulation of gene expression and protein translation, energy production, and antiviral response ...
Cardenas-Rodriguez, Mauricio, Chatzi, Afroditi, Tokatlidis, Kostas   +2 more
core   +1 more source

Central nervous system recurrence in a patient treated for acute promyelocytic leukemia, resulting in sideroblastic anemia: A case report

World Journal of Hematology, 2022
BACKGROUND Previous cases that have been stated in this article have displayed that around 1% to 7% of patients that have been treated with chemotherapy for acute promyelocytic leukemia developed myelodysplastic syndrome or acute myeloid leukemia.
Haroon Nawaz, Ayesha A. Choudhry, William Morse   +2 more
semanticscholar   +1 more source

Clinical studies on iron metabolism of erythroblasts in preleukemic stage [PDF]

, 1974
The appearance of sideroblasts in hypoplastic anemia (HAl and acute myelocytic leukemia (AML), together with their sideroblastograms, was studied. Hematological studies on cases with type III sideroblast dominance by sideroblastograms produced the ...
Kimura, Ikuro, Sugiyama, Motoharu, Takahashi, lsao   +2 more
core   +1 more source

SLC25A38 congenital sideroblastic anemia: Phenotypes and genotypes of 31 individuals from 24 families, including 11 novel mutations, and a review of the literature

Human Mutation, 2021
The congenital sideroblastic anemias (CSAs) are a heterogeneous group of inherited disorders of erythropoiesis characterized by pathologic deposits of iron in the mitochondria of developing erythroblasts.
M. Heeney, Simon Berhe, D. Campagna, Joseph H. Oved, P. Kurre, Peter Shaw, J. Teo, M. A. Shanap, H. Hassab, B. Glader, Sanjay Shah, A. Yoshimi, A. Ameri, J. Antin, J. Boudreaux, M. Briones, K. Dickerson, C. Fernandez, R. Farah, H. Hasle, Siobán B. Keel, T. Olson, J. Powers, M. Rose, Akiko Schimamura, S. Bottomley, M. Fleming   +26 more
semanticscholar   +1 more source

When Ring Sideroblasts on Bone Marrow Smears Are Inconsistent with the Diagnosis of Myelodysplastic Neoplasms

Diagnostics, 2022
Ring sideroblasts are commonly seen in myelodysplastic neoplasms and are a key condition for identifying distinct entities of myelodysplastic neoplasms according to the WHO classification.
Sandrine Girard, Franck Genevieve, Emmanuelle Rault, Odile Fenneteau, Jean-François Lesesve   +4 more
doaj   +1 more source

TRNT1 deficiency: clinical, biochemical and molecular genetic features [PDF]

, 2016
BACKGROUND: TRNT1 (CCA-adding transfer RNA nucleotidyl transferase) enzyme deficiency is a new metabolic disease caused by defective post-transcriptional modification of mitochondrial and cytosolic transfer RNAs (tRNAs).
Chong, WK, Clayton, PT, Fassone, E, Footitt, E, Kleta, R, Mills, PB, Minczuk, M, Niazi, R, Pearce, S, Plagnol, V, Powell, CA, Rahman, S, Saldanha, JW, Taanman, JW, Wedatilake, Y   +14 more
core   +2 more sources

Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors [PDF]

, 2018
OBJECTIVES: To characterise the clinical features, immune manifestations and molecular mechanisms in a recently described autoinflammatory disease caused by mutations in TRNT1, a tRNA processing enzyme, and to explore the use of cytokine inhibitors in ...
et al, Giannelou, Angeliki, Pachlopnik, Jana M, Prader, Seraina   +3 more
core   +1 more source