Results 151 to 160 of about 837,779 (311)

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo   +10 more
wiley   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Tramadol use in a patient with Brugada syndrome and morphine allergy: a case report

open access: yesJournal of Pain Research, 2018
Cengiz Sahutoglu, Seden Kocabas, Fatma Zekiye Askar Ege University School of Medicine, Department of Anesthesiology and Reanimation, Izmir, Turkey Abstract: Brugada syndrome is a rare syndrome characterized by arrhythmias and sudden death, particularly ...
Sahutoglu C, Kocabas S, Askar FZ
doaj  

Extracellular Matrix‐Mediated Crosslinking of Adhesive Hyaluronic Acid Patch for Treating Volumetric Muscle Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon   +6 more
wiley   +1 more source

Universal Hydrogel Carrier Enhances Bone Graft Success: Preclinical and Clinical Evaluation

open access: yesAdvanced Healthcare Materials, EarlyView.
TX hydrogel improves the delivery of different types of particulate bone grafts, maintaining them at the implantation sites, and resulting in favorable bone regenerative outcomes. Abstract Orthopedic, maxillofacial, and complex dentoalveolar bone grafting procedures that require donor‐site bone harvesting can be associated with post‐surgical ...
Dax Calder   +9 more
wiley   +1 more source

Ovarian Function Restoration with Biomimetic Scaffold Incorporating Angiogenic Molecules and Antioxidant in Chemotherapy‐Induced Perimenopausal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim   +8 more
wiley   +1 more source

Deciphering the Enigma: Lignocaine Resistance After Scorpion Envenomation. [PDF]

open access: yesCureus
Madheswaran K   +4 more
europepmc   +1 more source

Hydrogel Adhesive Integrated‐Microstructured Electrodes for Cuff‐Free, Less‐Invasive, and Stable Interface for Vagus Nerve Stimulation

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, a cuff‐free, less‐invasive surgical approach for vagus nerve stimulation (VNS) by combining ultrathin Y‐shaped kirigami electrodes is developed with a chemically cross‐linked hydrogel adhesive (hydrogel‐kirigami). Unlike conventional cuff implantation, which may damage nerves and nearby critical vessels, this new technique minimizes ...
Jae Young Park   +9 more
wiley   +1 more source

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