Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]
● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa+4 more
core +2 more sources
Effects of anesthesia on conventional and speckle tracking echocardiographic parameters in a mouse model of pressure overload [PDF]
Genetically‑modified mice are widely applied in cardiovascular studies as model organisms. Echocardiography is a key tool for evaluating cardiac and hemodynamic functions in mice.
Cao, Ming+7 more
core +1 more source
Activity-dependent plasticity of transmitter release from nerve terminals in rat fast and slow muscles [PDF]
Available under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported license.Peer reviewedPublisher ...
Bewick, Guy Smith+4 more
core +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
SENSORY REGRESSION TIME FROM SUBARACHNOID BLOCK WITH HYPERBARIC 0.75% BUPIVACAINE IN THE OBESE PATIENT [PDF]
The purpose of this study was to determine if obese patients have a different sensory regression time from subarachnoid block than non-obese patients using hyperbaric 0.75% bupivacaine. A quasi-experimental design was used. Twenty patients were separated
Hilton, George Leslie
core +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery [PDF]
BACKGROUND: Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients.
Baraka, Anis+6 more
core +2 more sources
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun+5 more
wiley +1 more source
Maxillary nerve block: A comparison between the greater palatine canal and high tuberosity approaches. [PDF]
Aim: Analgesia and anxiolysis during dental procedures are important for dental care and patient compliance. This study aims to compare two classical maxillary nerve block (MNB) techniques: the greater palatine canal (GPC) and the high tuberosity (HT ...
Bacci, C+6 more
core
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source