Results 121 to 130 of about 105,924 (291)

Protocol for measuring protein synthesis in specific cell types in the mouse brain using in vivo non-canonical amino acid tagging

open access: yesSTAR Protocols
Summary: The fluorescent non-canonical amino acid tagging (FUNCAT) technique has been used to visualize newly synthesized proteins in cell lines and tissues.
Mehdi Hooshmandi   +9 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Effects of dental treatment under general anesthesia on the oral health quality of life and dental fear of preschool children: a systematic review and meta-analysis

open access: yesBMC Oral Health
Objectives In this review, we aimed to determine the effects of dental treatment under general anesthesia on the oral health-related quality of life and dental fear of preschool children. Materials and methods A comprehensive electronic search of PubMed,
Tu Huang   +3 more
doaj   +1 more source

A comparison of the antimicrobial efficacy of silver diamine fluoride and silver nitrate: an in vitro study [PDF]

open access: yes, 2018
A COMPARISON OF THE ANTIMICROBIAL EFFICACY OF SILVER DIAMINE FLUORIDE AND SILVER NITRATE: AN IN VITRO STUDY By: Nicholas L Luke, D.D.S. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at ...
Luke, Nicholas L
core   +2 more sources

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

open access: yesAdvanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen   +10 more
wiley   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

open access: yesAdvanced Science, EarlyView.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang   +4 more
wiley   +1 more source

Dental local anesthesia in Family Health Units: use, pain and associated factors

open access: yesRevista Dor
BACKGROUND AND OBJECTIVES: In spite of the relevance of controlling pain during dental procedures and of the fundamental role of Family Health Units in the Brazilian health system, there are few studies integrating both subjects.
Etenildo Dantas Cabral
doaj   +1 more source

The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep

open access: yesAdvanced Science, EarlyView.
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller   +3 more
wiley   +1 more source

Changes in children′s oral health related quality of life following dental treatment under general anesthesia

open access: yesDental Research Journal, 2009
Background: Children′s oral health related quality of life (OHRQoL) evaluates the impacts of oral daily activities of children and family on quality of life.
Seyed Ebrahim Jabarifar   +3 more
doaj  

TRICHLORETHYLENE IN DENTAL ANESTHESIA [PDF]

open access: yesSouthern Medical Journal, 1944
openaire   +1 more source

Home - About - Disclaimer - Privacy