Results 121 to 130 of about 54,521 (292)

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao   +6 more
wiley   +1 more source

An international Delphi survey and consensus meeting to define the core outcome set for trigeminal neuralgia clinical trials

open access: yesEuropean Journal of Pain, Volume 27, Issue 1, Page 86-98, January 2023., 2023
Abstract Background Trigeminal neuralgia (TN) is an excruciating unilateral facial pain, which negatively affects patient's quality of life. Historically, it has been difficult to compare treatment efficacy due to the lack of standardized outcomes. In addition, patients' perspective has seldomly been acknowledged.
Carolina Venda Nova   +3 more
wiley   +1 more source

Haptic bilateral teleoperation system for free-hand dental procedures [PDF]

open access: yesarXiv
Free-hand dental procedures are typically repetitive, time-consuming and require high precision and manual dexterity. Dental robots can play a key role in improving procedural accuracy and safety, enhancing patient comfort, and reducing operator workload.
arxiv  

Alterations in gut microbiota and metabolites contribute to postoperative sleep disturbances

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we classified postoperative patients into poor sleepers (PS) and good sleepers (GS) based on the bispectral index (BIS), and transplanted their fecal microbiota to pseudo‐germ‐free rats to analyze the sleep changes in rats and the potential mechanism.
Hui Zhong   +7 more
wiley   +1 more source

Migraine in university students: A systematic review and meta‐analysis

open access: yesEuropean Journal of Pain, Volume 27, Issue 1, Page 14-43, January 2023., 2023
Abstract Background Migraine is a complex, neurobiological disorder usually presenting as a unilateral, moderate to severe headache accompanied by sensory disturbances. Migraine prevalence has risen globally, affecting 14% of individuals and 16% of students and carries many negative impacts in both cohorts.
Orla Flynn   +2 more
wiley   +1 more source

Enhanced Pediatric Dental Segmentation Using a Custom SegUNet with VGG19 Backbone on Panoramic Radiographs [PDF]

open access: yesarXiv
Pediatric dental segmentation is critical in dental diagnostics, presenting unique challenges due to variations in dental structures and the lower number of pediatric X-ray images. This study proposes a custom SegUNet model with a VGG19 backbone, designed explicitly for pediatric dental segmentation and applied to the Children's Dental Panoramic ...
arxiv  

IKIMOKYKLINIO AMŽIAUS VAIKŲ TĖVŲ ŽINIOS APIE DANTŲ GYDYMĄ SEDACIJOS IR BENDROSIOS NEJAUTROS ATVEJU BEI BURNOS PRIEŽIŪRĄ = PARENTS KNOWLEDGE ABOUT PRESCHOOL CHILDREN DENTAL TREATMENT UNDER SEDATION AND GENERAL ANESTHESIA AND MOUTH CARE

open access: yesTaikomieji tyrimai studijose ir praktikoje, 2019
Sedation and general anesthesia are based on pharmacological treatment of child behaviour. The main purpose of sedation and general anesthesia processes is the management of children's behaviour and pain control.
Rima Adomaitienė   +1 more
doaj  

Incidence of traumatic dental injuries associated with orotracheal intubation in general anesthesia in children during mixed dentition in Damascus, Syria: a prospective longitudinal study

open access: yesBDJ Open
Objectives Endotracheal tube intubation by laryngoscope during general anesthesia is a safe procedure with a few complications. However, it may cause some damage to the oral cavity structures, which leads to postoperative pain and discomfort.
Mohammed N. Al-Shiekh   +3 more
doaj   +1 more source

Establishment of rat model for aspiration pneumonia and potential mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu   +7 more
wiley   +1 more source

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