Results 161 to 170 of about 488,543 (329)

Inclusion of health equity variables in UK national anaesthesia projects

Anaesthesia, EarlyView.
Sarah Hudson, Akshay Shah, Søren Kudsk‐Iversen   +2 more
wiley   +1 more source

Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel, Chaitali Ghosh, Kathryn Bisaha, Jean Khoury, Ashley Nemes‐Baran, Ingmar Blumcke, Imad Najm   +6 more
wiley   +1 more source

Posterior injectate spread following lumbar erector spinae plane blockade

Anaesthesia, EarlyView.
Gillian D. Saffy, Gillian Lamacraft, Jacques Janse van Rensburg, Je'nine Horn‐Lodewyk   +3 more
wiley   +1 more source

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

Epilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe, Steeve Thirard, Juri Aparicio Arias, Leila Makrini, Florence Fauvelle, Emmanuelle Beyne, Alexandra Dauvé, Tristan Bouschet, Emmanuel Valjent, Federica Bertaso   +9 more
wiley   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

Equine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan, J. Burns, E. John, M. Buote   +3 more
wiley   +1 more source

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

Equine Veterinary Education, EarlyView.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch, C. Frank, J. B. Daniels, E. Acutt, E. Contino   +4 more
wiley   +1 more source

Silent pressure: Unveiling spinal lymphoma in horses and its parallels to other species

Equine Veterinary Education, EarlyView.
Summary Though the nervous system is an uncommon location for lymphoma, the disease should remain a differential diagnosis in some cases of ataxia in equids. Diagnosis of lymphoma can be challenging, although a combination of cytology, histopathology and immunophenotyping can aid in definitive diagnosis and therefore more accurately guide treatment and
H. E. Taylor, D. Luethy
wiley   +1 more source

Improving mare fertility via broad ligament imbrication with barbed suture and intracorporeal suturing device

Equine Veterinary Education, EarlyView.
Summary In this short case series, we report the outcome of four mares undergoing mesometrial imbrication (uteropexy) using barbed suture and an automated laparoscopic suturing device. Medical records of four mares infertile because of delayed uterine clearance (DUC) that underwent laparoscopic mesometrial imbrication to elevate a vertically positioned
A. del Rincon, J. M. O'Leary, A. Derham, C. Hawkes   +3 more
wiley   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Needle bevel orientation does not affect diffusion of contrast medium during perineural injection of the lateral palmar/plantar nerve and lateral palmar metacarpal/plantar metatarsal nerves

Equine Veterinary Education, EarlyView.
Summary Background Perineural anaesthesia is used to localise pain in horses presenting with lameness. Diffusion of local anaesthetics during perineural analgesia complicates clinical interpretation. Needle bevel orientation has been shown to affect drug diffusion in humans.
V. Knopp, A. Dockery, S. Giancola, J. Bonner, S. Johnson, E. Crowfoot, K. L. Ellis   +6 more
wiley   +1 more source