Results 1 to 10 of about 1,418,408 (318)

The thermodynamics of general anesthesia [PDF]

Biophys. J. 92 (2007) 3159-3165, 2006
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton
Abelho, Andrew D. Jackson, Boheim, Cantor, Cantor, Cantor, Cantor, Cruzeiro-Hansson, Ebel, Firestone, Firestone, Franks, Franks, Galla, Halsey, Heimburg, Heimburg, Jain, Johnson, Kamaya, Kaminoh, Kaminoh, Katz, Kendig, Kharakoz, Kinnunen, Kobatake, Kreienbühl, Langerman, Lee, Lee, Meyer, Moss, Overton, Papahadjopoulos, Peoples, Punnia-Moorthy, Ritchie, Roth, Silbey, Spyropoulos, Thomas Heimburg, Trudell, Träuble, Träuble, Urban, van de Vossenberg   +46 more
arxiv   +11 more sources

General anesthesia reduces complexity and temporal asymmetry of the informational structures derived from neural recordings in Drosophila [PDF]

Phys. Rev. Research 2, 023219 (2020), 2019
We apply techniques from the field of computational mechanics to evaluate the statistical complexity of neural recording data from fruit flies. First, we connect statistical complexity to the flies' level of conscious arousal, which is manipulated by general anesthesia (isoflurane).
Cohen, Dror, Leung, Angus, Modi, Kavan, Muñoz, Roberto N., Pollock, Felix A., Tsuchiya, Naotsugu, van Swinderen, Bruno, Zecevik, Aidan   +7 more
arxiv   +3 more sources

Stabilizing membrane domains antagonizes n-alcohol anesthesia [PDF]

Biophysical Journal, Volume 111, Issue 3, 9 August 2016, Pages 537-545, 2016
Diverse molecules induce general anesthesia with potency strongly correlated both with their hydrophobicity and their effects on certain ion channels. We recently observed that several n-alcohol anesthetics inhibit heterogeneity in plasma membrane derived vesicles by lowering the critical temperature ($T_c$) for phase separation.
Brooks, NJ, Gray, E, Gray, EM, Machta, BB, McCarthy, NLC, Miller, AL, Nouri, M, Veatch, SL   +7 more
arxiv   +5 more sources

Retrospective analysis of the feasibility and safety of external jugular vein cannulation in surgical patients [PDF]

Anesthesia and Pain Medicine, 2023
Background Establishing intravenous (IV) access is an essential procedure in surgical patients. External jugular vein (EJV) cannulation can be a good alternative for patients for whom it is difficult to establish peripheral IV access.
Jae-Woo Ju, Yoonbin Hwang, Ho-Jin Lee
doaj   +1 more source

Numbness of the lower lip following urological surgery under general anesthesia – A case report – [PDF]

Anesthesia and Pain Medicine, 2021
Background Peripheral nerve injury is a complication that can occur after general anesthesia. It significantly impairs the patient’s quality of life and may lead to permanent disability.
Su Yeon Kim, Yunhee Lim, Geon Hyeong Bae, Dae Hee Suh, Kye-Min Kim   +4 more
doaj   +1 more source

Efficacy of stylet angulation at the holding position during tracheal intubation with a videolaryngoscope: a randomized controlled trial

Scientific Reports, 2021
The aim of this randomized controlled trial was to determine the efficacy of stylet angulation at the holding position during tracheal intubation with a McGRATH MAC videolaryngoscope.
Ryo Wakabayashi, Yuki Shiko, Tomofumi Kodaira, Yuko Shiroshita, Hitomi Otsuka, Kosuke Baba, Norimasa Hishinuma   +6 more
doaj   +1 more source

Pharmacodynamic modeling of moderate sedation and rationale for dosing using midazolam, propofol and alfentanil

BMC Pharmacology and Toxicology, 2023
Purpose Regulations have broadened to allow moderate sedation administration for gastrointestinal endoscopy by non-anesthesia personnel. The line between moderate and deep sedation is ambiguous.
Jing-Yang Liou, I-Ting Kuo, Weng-Kuei Chang, Chien-Kun Ting, Mei-Yung Tsou   +4 more
doaj   +1 more source

Development and prospective validation of postoperative pain prediction from preoperative EHR data using attention-based set embeddings

npj Digital Medicine, 2023
Preoperative knowledge of expected postoperative pain can help guide perioperative pain management and focus interventions on patients with the greatest risk of acute pain.
Ran Liu, Rodrigo Gutiérrez, Rory V. Mather, Tom A. D. Stone, Laura A. Santa Cruz Mercado, Kishore Bharadwaj, Jasmine Johnson, Proloy Das, Gustavo Balanza, Ekenedilichukwu Uwanaka, Justin Sydloski, Andrew Chen, Mackenzie Hagood, Edward A. Bittner, Patrick L. Purdon   +14 more
doaj   +1 more source

History of anesthesia usage in dentistry [PDF]

Stomatološki glasnik Srbije, 2005
Since prehistoric times, man has sought ways to lessen pain. With varying degrees of success he has utilized: opium, nerve compresses, cold, hypnosis, etc.
Koković Vladimir
doaj   +1 more source

Oxygen conditions oscillating between hypoxia and hyperoxia induce different effects in the pulmonary endothelium compared to constant oxygen conditions

Physiological Reports, 2021
The pulmonary endothelium is an immediate recipient of high oxygen concentrations upon oxygen therapy and mediates down‐stream responses. Cyclic collapse and reopening of atelectatic lung areas during mechanical ventilation with high fractions of ...
Peter Wohlrab, Michael Johann Danhofer, Wolfgang Schaubmayr, Akos Tiboldi, Katharina Krenn, Klaus Markstaller, Roman Ullrich, Klaus Ulrich Klein, Verena Tretter   +8 more
doaj   +1 more source