Results 41 to 50 of about 11,601,727 (294)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Anesthetic Implications for Cesarean Section in a Parturient with Complex Congenital Cyanotic Heart Disease

Case Reports in Anesthesiology, 2018
The discordance between increased physiological demand during pregnancy and congenital cardiac pathology of a parturient is a perilous threat to the maternal-fetal well-being.
Huili Lim, Chuen Jye Yeoh, Jerry Tan, Harikrishnan Kothandan, May U. S. Mok   +4 more
doaj   +1 more source

Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries: The Pathfinder Feasibility Trial [PDF]

, 2021
Multimodal general anesthesia (MMGA) is a strategy that utilizes the well-known neuroanatomy and neurophysiology of nociception and arousal control in designing a rational and clinical practical paradigm to regulate the levels of unconsciousness and ...
Shanker, Akshay, Senthilnathan, Venkatachalam, Abel, John H, Schamberg, Gabriel, Sharkey, Aidan, Narayanan, Shilpa, Subramaniam, Balachundhar, Mathur, Pooja, Work, Erin, Rangasamy, Valluvan, Abel, John H., Brown, Emery N., Bose, Ruma, Brown, Emery Neal, Balachundhar Subramaniam, Ruma Bose, Venkatachalam Senthilnathan, Erin Work, Gabriel Schamberg, Aidan Sharkey, Emery N. Brown, John H. Abel, Akshay Shanker, Shilpa Narayanan, Valluvan Rangasamy, Pooja Mathur   +25 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Lung (extracorporeal CO2 removal) and renal (continuous renal replacement therapy) support: the role of ultraprotective strategy in Covid 19 and non-Covid 19 ARDS. A case-control study

Journal of Anesthesia, Analgesia and Critical Care
Background Preliminary studies suggest that moderate ARDS and acute renal failure might benefit from extracorporeal CO2 removal (ECCO2R) coupled with CRRT. However, evidence is limited and potential for this coupled treatment may need to be explored. The
Daniela Pasero, Laura Pistidda, Davide Piredda, Corrado Liperi, Andrea Cossu, Raffaella Esposito, Angela Muroni, Cristiano Mereu, Carlino Rum, Gian Pietro Branca, Franco Mulas, Mariangela Puci, Giovanni Sotgiu, Pierpaolo Terragni   +13 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Comparing the safety and efficacy of remimazolam-based total intravenous anesthesia versus volatile agent-based anesthesia: a meta-analysis of randomized controlled trials [PDF]

Korean Journal of Anesthesiology
Background Remimazolam is a novel short-acting benzodiazepine that has recently been used for general anesthesia. This study compared the safety and efficacy of remimazolam-based total intravenous anesthesia (TIVA) and volatile agent-based anesthesia in ...
Ji-In Park, Hyo-Seok Na, Keum-O Lee, Jung-Hee Ryu, Hyun-Jung Shin   +4 more
doaj   +1 more source

Department of Anesthesia. University of Iowa. Spring 2009. [PDF]

, 2009
University of Iowa Department of Anesthesia ...

core  

General Anesthesia, Sleep, and Coma [PDF]

New England Journal of Medicine, 2010
This review discusses the clinical and neurophysiological features of general anesthesia and their relationships to sleep and coma, focusing on the neural mechanisms of unconsciousness induced by selected intravenous anesthetic drugs.
Schiff, Nicholas D., Brown, Emery N., Lydic, Emily K.   +2 more
openaire   +5 more sources