Results 151 to 160 of about 7,817,858 (363)

Microtubule-modulating drugs alter sensitivity to isoflurane in mice

BMC Anesthesiology
Background Microtubules (MTs) have been postulated as one of the molecular targets underlying loss of consciousness induced by inhalational anesthetics. Microtubule-targeting chemotherapy drugs and opioids affect MT stability and function.
Na Li, Zerong You, Yang Ren, Hyung Hwan Kim, Jinsheng Yang, Ge Li, Jason T. Doheny, Weihua Ding, Suyun Xia, Shiyu Wang, Xue Zhou, Xinbo Wu, Shiqian Shen, Yuanlin Dong, Zhongcong Xie, Lucy Chen, Jianren Mao, J. A. Jeevendra Martyn   +17 more
doaj   +1 more source

Studies on the mechanism of general anesthesia

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Anesthetics are used every day in thousands of hospitals to induce loss of consciousness, yet scientists and the doctors who administer these compounds lack a molecular understanding for their action.
M. A. Pavel, E. Petersen, Hao Wang, R. Lerner, S. Hansen, Steve Brohawn, Tiago Gil Oliveira   +6 more
semanticscholar   +1 more source

Mechanistic Insights into the Modulation of Voltage-Gated Ion Channels by Inhalational Anesthetics [PDF]

, 2015
General anesthesia is a relatively safe medical procedure, which for nearly 170 years has allowed life saving surgical interventions in animals and people.
Barber, Annika F., Carnevale, Vincenzo, Covarrubias, Manuel, Eckenhoff, Roderic G., Treptow, Werner   +4 more
core   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Hysteresis in anesthesia and recovery: Experimental observation and dynamical mechanism [PDF]

arXiv, 2020
The dynamical mechanism underlying the processes of anesthesia-induced loss of consciousness and recovery is key to gaining insights into the working of the nervous system. Previous experiments revealed an asymmetry between neural signals during the anesthesia and recovery processes.
arxiv  

Simultaneous Electroencephalography and Functional Magnetic Resonance Imaging of General Anesthesia [PDF]

, 2009
It has been long appreciated that anesthetic drugs induce stereotyped changes in electroencephalogram (EEG), but the relationships between the EEG and underlying brain function remain poorly understood.
Alkire, Alkire, Alkire, Alkire, Alkire, Angelone, Antognini, Bonhomme, Bonmassar, Calverley, Campagna, Cooper, Cox, Davis, Dilger, Doyle, Eger, Enlund, Evers, Fiset, Franks, Goodman, Grasshoff, Guimaraes, Hall, Harms, Harms, Heinke, Hemmings, Hoge, Kennedy, Kerssens, Lagerkranser, Matta, Matta, Newman, Percival, Plourde, Purdon, Schnider, Schnider, Shafer, Strebel, Thesen, Veselis, Werner, Wiklund   +46 more
core   +1 more source

Association of Higher Levels of High‐Sensitivity C‐Reactive Protein With Future Development of Psoriatic Arthritis in Psoriasis: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder, Xianwei Li, Vinod Chandran, Cheryl F. Rosen, Richard J. Cook, Dafna D. Gladman   +5 more
wiley   +1 more source

Pengaruh Pemberian Terapi Musik Klasik Terhadap Tekanan Darah Dan Denyut Jantung Pasien Pasca Operasi Dengan Anestesi Umum Di Rs Dr. Moewardi Surakarta [PDF]

, 2016
Homodynamic stability was an important indicator of an ideal anesthetic action and influence the anesthetic management plan. Management of complications of anesthesia in space can be recovered aware of pharmacology and complementary therapies as a ...
, Arief Wahyudi Jadmiko, S.Kep, Ns., , Arina Maliya S.Kep,M.Si.Med., Pradita, Nunung Arian   +2 more
core  

Methylphenidate Actively Induces Emergence from General Anesthesia [PDF]

, 2011
Background: Although accumulating evidence suggests that arousal pathways in the brain play important roles in emergence from general anesthesia, the roles of monoaminergic arousal circuits are unclear.
Brown, Emery N., Chemali, Jessica J., Cimenser, Aylin, Cotten, Joseph F., Solt, Ken, Wong, Kin F. K.   +5 more
core   +1 more source

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

Arthritis Care &Research, EarlyView.
Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras, Claire E. H. Barber, J. Antonio Aviña‐Zubieta, Hude Quan, Seungwon Lee, James A. King, Cheryl Barnabe   +6 more
wiley   +1 more source