Results 221 to 230 of about 72,384 (293)

Efficient analysis of toxicity and mechanisms of isoflurane on postoperative delirium by network toxicology and molecular docking

Neuroprotection, EarlyView.
Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai, Qing Nan, Menglu Xu, Hongbao Li   +3 more
wiley   +1 more source

Determination of the 90% Effective Dose of Remimazolam Continuous Infusion for Preventing Emergence Delirium in Pediatric Patients Undergoing Adenoidectomy or Adenotonsillectomy with Sevoflurane: A Biased Coin Up-and-Down Sequential Trial Design. [PDF]

Drug Des Devel Ther
Yang ZS, Li D, Jiang Y, Xiao F, Yan HY.
europepmc   +1 more source

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

Pediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding   +7 more
wiley   +1 more source

Analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive inguinal hernia surgery. [PDF]

World J Gastrointest Surg
Lou QX, Xu KP.
europepmc   +1 more source

Atomic Force Microscopy‐Based Nanomechanical Signatures for Staging Classification and Drug Response in Pulmonary Fibrosis

Small, EarlyView.
Atomic Force Microscopy (AFM) reveals nanomechanical fingerprints (NMFs) that track the progression of pulmonary fibrosis (PF) and response to therapy. These NMFs correlate with collagen I content and gene expression, offering a novel biomarker for disease staging and treatment monitoring.
Andreas Stylianou, Katerina Polemidiotou, Vassilis Alimisis, Fotios Mpekris, Chrysovalantis Voutouri, Meropi Mari, George Filippidis, Andreas Zachariades, Stylianos‐Vasileios Kontomaris, Paul P Sotiriadis, Vasiliki Gkretsi, Triantafyllos Stylianopoulos   +11 more
wiley   +1 more source

Effects of Motor-Evoked Potential Monitoring During Spine Surgery on the Length of Hospital Stay and Postoperative Acute Pain. [PDF]

Cureus
Taichi F, Mitobe Y, Baba Y, Tachibana N, Miyashita T.   +4 more
europepmc   +1 more source

Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma

Small Science, EarlyView.
Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim, Han Sol Lee, June Hong Ahn, Tae‐Wan Kwon, So‐Yeol Yoo, Donghyuk Seo, Sang Kyum Kim, Hee Ho Park, Seung‐Woo Cho, Wonhwa Lee, Jae‐Young Lee, Hong Nam Kim   +11 more
wiley   +1 more source

CO2, infections, and critical illnesses. [PDF]

Trauma Surg Acute Care Open
Coleman LS.
europepmc   +1 more source

Nanosecond Laser‐Assisted Direct Integration of Whitlockite onto Bone Implant Surfaces for Enhanced Bone Regeneration

Small Methods, EarlyView.
A laser‐assisted strategy enables the in situ formation of whitlockite coatings on bone implants through a magnesium calcium phosphate intermediate. This approach overcomes synthesis barriers, yielding bioactive surfaces that promote bone–implant integration and vascularization, offering a scalable route for next‐generation regenerative implants ...
Daehyeok Kwon, Hee Jae Hwang, Sun Hee Lee, Soon Jin Choi, Sangmin Song, Ji‐Young Lee, Hyeok Kim, Seung‐Hoon Um, Soyeon Park, Hyewon Kim, Yeon Jae Chang, Yu‐Chan Kim, Hojeong Jeon, Jimin Park, Hyung‐Seop Han   +14 more
wiley   +1 more source

Recovery Profiles and Well-Being Outcomes in Patients Undergoing Various Anaesthesia Techniques: A Systematic Review. [PDF]

Health Sci Rep
Bubshait AK.
europepmc   +1 more source