Results 221 to 230 of about 50,706 (302)

Inhaled 5-HT_1B _/1D Receptor Antagonist Attenuates Sumatriptan-Induced Sensitization of Capsaicin-Sensitive Lung Vagal Afferents: Implications for Preventing Sumatriptan-Associated Adverse Chest Symptoms. [PDF]

Compr Physiol
Chan NJ, Yuan ZF, Kuo CC, Hsu CC.
europepmc   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Preoperative Oral Rehydration Therapy Mitigates Circulatory Suppression During Anesthesia Induction: A Retrospective Study of 1,000 Elective Surgery Cases Exploring Appropriate Preoperative Intake Volume. [PDF]

Cureus
Taniguchi H, Kamada T, Sasaki T, Koga M.
europepmc   +1 more source

TREM2 in Macrophages Promotes Renal Fibrosis via Activation of β‐Catenin Signalling Pathway in Obstructive Nephropathy

Cell Proliferation, EarlyView.
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) promotes obstructive nephropathy progression by activating the β‐catenin signalling pathway, driving M2 macrophage polarisation, migration and fibrogenic gene expression. targeted inhibition of TREM2 thus represents a promising novel strategy against renal fibrosis.
Jia Wei, Zixia Li, Gengyu Du, Ting Chen, Min Yang, Zhen Yuan, Yidan Zheng, Xiang Yan   +7 more
wiley   +1 more source

Correction: Differential association of the 5-factor modified frailty index with postoperative pulmonary complications: specific prediction of infection risk after pulmonary lobectomy. [PDF]

Front Med (Lausanne)
Zheng Q, Wu Z, Du L, Chen A, Zhou J, Shi J, Lai Y, Chen W, Ke W, Xu H.   +9 more
europepmc   +1 more source

Single Cell Multi‐Omics Revealing the Important Role of MR1 Mediated MAIT Cells in Maintaining Rejection for Liver Transplantation

Cell Proliferation, EarlyView.
This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai, Xinqiang Li, Xin Zhou, Xueteng Wang, Zhuoyu Jia, Ruidong Ding, Yurong Luo, Ye Wang, Shipeng Li, Wenxing Sun, Dongxing Wu, Dahong Teng, Kai Zhao, Guanghui Pei, Jinzhen Cai, Bin Wu   +15 more
wiley   +1 more source

Influence of sevoflurane combined with propofol anesthesia on the anesthesia effect and adverse reactions in children with acute appendicitis. [PDF]

Open Med (Wars)
Zhang P, Zhang J, Chen F.
europepmc   +1 more source

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

Cell Proliferation, EarlyView.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao, Qiaonan Ye, Chengpeng Yang, Yuping Xie, Xuemei Long, Long Bai, Zhiyuan Zhang, Qianwei Li, Dan Tan, Jingang Xiao   +9 more
wiley   +1 more source

Conservative management of cranial cruciate ligament injury in an Asian small-clawed otter (Aonyx cinereus). [PDF]

J Vet Med Sci
Tomihari M, Murakami S, Tanaka T, Hasegawa T.   +3 more
europepmc   +1 more source

Retrospective case series of two‐stage folded paramedian forehead flap nasal reconstruction without cartilage grafts

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Full‐thickness nasal defects of the tip, soft triangle, and ala are commonly reconstructed using a paramedian forehead flap with cartilage grafts or an epithesis. However, these approaches may be associated with donor‐site morbidity and psychological burden.
Conrad Hempel, Viktor Schnabel, Jan‐Christoph Simon, Sonja Grunewald   +3 more
wiley   +1 more source