Results 81 to 90 of about 5,515,945 (353)

Safety Pharmacology Study of ET-26 Hydrochloride, a Potential Drug for Intravenous General Anesthesia, in Rats and Beagle Dogs

open access: yesFrontiers in Pharmacology, 2021
Background: ET-26 hydrochloride (ET-26HCl), a class 1 new drug, was developed to reserve the advantages of etomidate with a mild adrenocortical inhibition.Purpose: this study was to evaluate the potential adverse effects on the cardiovascular system of ...
YuJun Zhang   +17 more
doaj   +1 more source

Microwave amplitude reflecting instability of LFP electrode ground field is useful for consciousness state identification [PDF]

open access: yesarXiv, 2021
We recently developed original electroencephalogram indices focusing on microwaves of flattish period (named $\tau$), which correlated with volatile anesthesia concentration in dogs. However, this mechanism remains unclear. $\tau$ was defined as a subthreshold wave and burst wave was defined as an above-threshold wave.
arxiv  

The thermodynamics of general anesthesia [PDF]

open access: yesBiophys. J. 92 (2007) 3159-3165, 2006
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton
arxiv   +1 more source

The Effect of Local Anesthesia When Used in Dental Restorative Cases Under General Anesthesia on Control of Intraoperative Physiologic Parameters and Post-Operative Comfort [PDF]

open access: yes, 2021
Purpose: To determine the effect of local anesthesia on post-operative pain and physiologic parameters intraoperatively in patients undergoing dental care under general anesthesia.
Skarda, Kathryn S
core   +1 more source

Effectiveness of a Telephone‐Delivered Walk With Ease Program on Arthritis‐Related Symptoms, Function, and Activity: A Randomized Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Walk With Ease (WWE) is a six‐week arthritis‐appropriate evidence‐based physical activity program traditionally offered in a face‐to‐face format. Because many populations encounter participation barriers to in‐person programs, WWE was modified for telephone delivery (WWE‐T).
Christine A. Pellegrini   +5 more
wiley   +1 more source

Dexmedetomidine with different concentrations added to local anesthetics in erector spinae plane block: a meta-analysis of randomized controlled trials

open access: yesFrontiers in Medicine
BackgroundDexmedetomidine has been used as a perineural local anesthetic (LA) adjuvant to facilitate the potency of erector spinal plane block (ESPB). This quantitative review aimed to evaluate whether perineural dexmedetomidine for ESPB can improve the ...
Qian Li   +8 more
doaj   +1 more source

Effect of Local Anesthesia on Postoperative Pain with General Anesthesia [PDF]

open access: yes, 2012
Purpose: The aim of this study was to determine if the use of local anesthesia with general anesthesia results in less postoperative pain. The alternative hypothesis is that children will experience less postoperative discomfort when utilizing ...
Campbell, Belinda
core   +2 more sources

Percutaneous Nephrolithotomy under Local Infiltration Anesthesia in Kneeling Prone Position for a Patient with Spinal Deformity [PDF]

open access: yes, 2020
Urolithiasis, a common condition in patients with spinal deformity, poses a challenge to surgical procedures and anesthetic management. A 51-year-old Chinese male presented with bilateral complex renal calculi.
Huang, Peng   +5 more
core   +1 more source

American College of Rheumatology Guidance Statements for Addressing Mental Health Concerns in Youth With Pediatric Rheumatologic Diseases

open access: yesArthritis Care &Research, EarlyView.
Objective Pediatric rheumatologic diseases (PRDs) are characterized by high rates of anxiety and depression known to impact health‐related outcomes. We present guidance statements to assess and manage mental health concerns for youth with PRDs in pediatric rheumatology practice.
Natoshia R. Cunningham   +21 more
wiley   +1 more source

Rapid quantification and PK-PD modeling of rocuronium bromide in beagles using portable mass spectrometer

open access: yesFrontiers in Veterinary Science
Monitoring rocuronium bromide (Rocur) concentrations is crucial for assessing muscle relaxation in clinical anesthesia. However, no suitable instruments are currently available. This study explores the application of a portable mass spectrometer (MS) for
Xiaoxiao Li   +9 more
doaj   +1 more source

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