Results 51 to 60 of about 15,072 (282)

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Optimal programmed intermittent epidural bolus volume for dural puncture epidural labor analgesia in patients with gestational hypertension: a biased-coin up-and-down sequential allocation trial

Frontiers in Medicine
BackgroundThis study aimed to evaluate the effective programmed intermittent epidural bolus (PIEB) volume and the efficacy of dural puncture epidural (DPE) for labor analgesia in patients with gestational hypertension (GH).MethodsFifty primiparous women ...
Binghui Zhang, Hongyang Zhang, Yuan Wu, Kai Zhao, Yancen Meng   +4 more
doaj   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

USE OF FLUIDS AND VASOPRESSORS IN THE PREVENTION AND MANAGEMENT OF THE SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING SCHEDULED CESAREAN SECTION IN COLOMBIAN WOMEN (IN SPANISH)

Revista Ciencias Biomédicas, 2014
Introduction: during the scheduled cesarean section, the main side effect of the spinal anesthesia is the spinal anesthesia-induced hypotension (SAIH).
Marrugo-Marrugo José, Granados-Vergara Lina, Marrugo-Vergara Jahaira   +2 more
doaj  

Maternal mortality due to obstetric hemorrhage by surgical injury during cesarean section: A nationwide study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Obstetric hemorrhage remains a largely preventable cause of maternal mortality globally. The contribution of uterine atony to hemorrhage‐related maternal mortality has decreased in France, while the contribution of other causes of obstetric ...
Pauline L. M. deVries, Eric Verspyck, Estelle Morau, Monica Saucedo, Catherine Deneux‐Tharaux, the ENCMM study group   +5 more
doaj   +1 more source

Construction of a nomogram prediction model for the influencing factors for spinal nerve injury in elderly parturients after intraspinal block [PDF]

精准医学杂志
Objective To establish a nomogram model for predicting the influence factors for spinal nerve injury in elderly parturients after intraspinal block. Methods A total of 480 elderly parturients who received intraspinal block for delivery in our hospital ...
SHI Yu, YUE Xiuqin, WANG Zhen
doaj   +1 more source

Maternity Care and Consumer-Driven Health Plans [PDF]

, 2007
Compares out-of-pocket costs of maternity care under consumer-driven health plans (CDHP) to a traditional health insurance plan. Explores related factors including prenatal care coverage and unpredictability of costs for delivery and hospital ...
Alina Salganicoff, Karen Pollitz, Mila Kofman, Usha Ranji   +3 more
core  

Epidural Analgesia Decreases Narcotic Requirements in Low Level Spina Bifida Patients Undergoing Urologic Laparotomy for Neurogenic Bladder and Bowel [PDF]

, 2018
Purpose Concern of anatomical anomalies and worsening neurologic symptoms has prevented widespread use of epidural catheters in patients with low level spina bifida (LLSB). We hypothesize that thoracic epidural placement in the T9-T10 interspace is safe
Cain, Mark P., Green, Morton C., Horn, Nicole D., Misseri, Rosalia, Monn, M. Francesca, Roth, Joshua D., Whittaker, Stephanie C.   +6 more
core   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Challenges in practice and training structure of residents in obstetric anaesthesia: a perspective from teaching hospitals in Sindh province of Pakistan

Journal of the Pakistan Medical Association
Objective: To document information on the available obstetric anaesthesia services and structure of resident training in a Pakistani setting. Method: The survey was conducted from June to September 2018 across the Sindh province of Pakitan after ...
Fauzia Anis Khan, Saeeda Haider, Nighat Abbas, Saleh Khaskheli, Ahmed Uddin Soomro, Safia Zafar Siddiqui   +5 more
doaj   +1 more source