Results 61 to 70 of about 168,965 (305)

Cardiac arrest in a child during a combined general epidural anesthesia procedure [PDF]

, 2005
An increased risk of perioperative cardiac arrest in children, in comparison to adults, has been recognized. A number of factors associated with perioperative cardiac arrest have been identified, including young age, comorbidities, and emergency ...
Soenarjo, Soenarjo, Soemantri,, A, Sidhartani,, M, Siahaan, Edwin MP, Prabakti, Yudhi   +4 more
core   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Efficacy and safety of nalbuphine for dural puncture epidural labor analgesia [PDF]

精准医学杂志
Objective To investigate the efficacy and safety of nalbuphine for dural puncture epidural labor analgesia. Methods A total of 319 primiparous women with a full-term single fetus who received trial of labor were enrolled, and according to the drug used ...
LI Xiaozheng, WANG Xuemei, LI Jingzhu, YU Wengang, BI Yanlin, TAO Hong
doaj   +1 more source

Identification of Sleep Medicine and Anesthesia Core Topics for Anesthesia Residency: A Modified Delphi Technique Survey

, 2021
BACKGROUND: Sleep disorders affect up to 25% of the general population and are associated with increased risk of adverse perioperative events. The key sleep medicine topics that are most important for the practice of anesthesiology have not been well ...
Wong, J, Singh, M, Auckley, D, Jonsson, Fagerlund M,, Gali, B, Joshi, GP, Charchaflieh, JG, Berezin, L, Nagappa, M, Clivatti, J   +9 more
core   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Optimal programmed intermittent epidural bolus volume for dural puncture epidural labor analgesia in patients with gestational hypertension: a biased-coin up-and-down sequential allocation trial

Frontiers in Medicine
BackgroundThis study aimed to evaluate the effective programmed intermittent epidural bolus (PIEB) volume and the efficacy of dural puncture epidural (DPE) for labor analgesia in patients with gestational hypertension (GH).MethodsFifty primiparous women ...
Binghui Zhang, Hongyang Zhang, Yuan Wu, Kai Zhao, Yancen Meng   +4 more
doaj   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Anesthetic Considerations for Labor and Delivery in Cancer Patients: A Review [PDF]

Middle East Journal of Cancer
Background: The trend of postponing childbirth has led to an increased incidence of cancer diagnoses during pregnancy, including breast cancer, cervical cancer, lymphoma, ovarian cancer, and melanoma.
Fatemeh Shafiei
doaj  

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Construction of a nomogram prediction model for the influencing factors for spinal nerve injury in elderly parturients after intraspinal block [PDF]

精准医学杂志
Objective To establish a nomogram model for predicting the influence factors for spinal nerve injury in elderly parturients after intraspinal block. Methods A total of 480 elderly parturients who received intraspinal block for delivery in our hospital ...
SHI Yu, YUE Xiuqin, WANG Zhen
doaj   +1 more source