Results 51 to 60 of about 14,553 (312)

Maternal mortality due to obstetric hemorrhage by surgical injury during cesarean section: A nationwide study

open access: yesActa Obstetricia et Gynecologica Scandinavica
Introduction Obstetric hemorrhage remains a largely preventable cause of maternal mortality globally. The contribution of uterine atony to hemorrhage‐related maternal mortality has decreased in France, while the contribution of other causes of obstetric ...
Pauline L. M. deVries   +5 more
doaj   +1 more source

Efficacy and safety of nalbuphine for dural puncture epidural labor analgesia [PDF]

open access: yes精准医学杂志
Objective To investigate the efficacy and safety of nalbuphine for dural puncture epidural labor analgesia. Methods A total of 319 primiparous women with a full-term single fetus who received trial of labor were enrolled, and according to the drug used ...
LI Xiaozheng, WANG Xuemei, LI Jingzhu, YU Wengang, BI Yanlin, TAO Hong
doaj   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

USE OF FLUIDS AND VASOPRESSORS IN THE PREVENTION AND MANAGEMENT OF THE SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING SCHEDULED CESAREAN SECTION IN COLOMBIAN WOMEN (IN SPANISH)

open access: yesRevista Ciencias Biomédicas, 2014
Introduction: during the scheduled cesarean section, the main side effect of the spinal anesthesia is the spinal anesthesia-induced hypotension (SAIH).
Marrugo-Marrugo José   +2 more
doaj  

Optimal programmed intermittent epidural bolus volume for dural puncture epidural labor analgesia in patients with gestational hypertension: a biased-coin up-and-down sequential allocation trial

open access: yesFrontiers in Medicine
BackgroundThis study aimed to evaluate the effective programmed intermittent epidural bolus (PIEB) volume and the efficacy of dural puncture epidural (DPE) for labor analgesia in patients with gestational hypertension (GH).MethodsFifty primiparous women ...
Binghui Zhang   +4 more
doaj   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Construction of a nomogram prediction model for the influencing factors for spinal nerve injury in elderly parturients after intraspinal block [PDF]

open access: yes精准医学杂志
Objective To establish a nomogram model for predicting the influence factors for spinal nerve injury in elderly parturients after intraspinal block. Methods A total of 480 elderly parturients who received intraspinal block for delivery in our hospital ...
SHI Yu, YUE Xiuqin, WANG Zhen
doaj   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

open access: yesAdvanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole   +17 more
wiley   +1 more source

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata   +4 more
wiley   +1 more source

Anesthetic Considerations for Labor and Delivery in Cancer Patients: A Review [PDF]

open access: yesMiddle East Journal of Cancer
Background: The trend of postponing childbirth has led to an increased incidence of cancer diagnoses during pregnancy, including breast cancer, cervical cancer, lymphoma, ovarian cancer, and melanoma.
Fatemeh Shafiei
doaj  

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