Results 101 to 110 of about 162,021 (290)

Calibrated forceps model of spinal cord compression injury. [PDF]

, 2015
Compression injuries of the murine spinal cord are valuable animal models for the study of spinal cord injury (SCI) and spinal regenerative therapy.
Ariza, Jeanelle, Martínez-Cerdeño, Verónica, McDonough, Ashley, Monterrubio, Angela   +3 more
core   +2 more sources

Spinal Anesthesia in Pediatrics

, 2022
The survival of preterm newborn patients (PNB) depends in a great extent on the anesthetic technique used. Spinal anesthesia (SA) is considered the best-tolerated regional anesthetic method for highly unstable newborn infants (NB) with high risk of complications during the perioperative period.
Karen L. Iñiguez-Lopéz, Yolanda M. Martínez-Barragán, Enrique Hernández-Cortez   +2 more
openaire   +4 more sources

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

Comparison of general anesthesia with endotracheal intubation, combined spinal-epidural anesthesia, and general anesthesia with laryngeal mask airway and nerve block for intertrochanteric fracture surgeries in elderly patients: a retrospective cohort study

BMC Anesthesiology, 2019
Background There is no consensus on the optimal anesthesia method for intertrochanteric fracture surgeries in elderly patients. Our study aimed to compare the hemodynamics and perioperative outcomes of general anesthesia with endotracheal intubation ...
Yang Liu, Mang Su, Wei Li, Hao Yuan, Cheng Yang   +4 more
doaj   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

Advanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu, Qi Huang, Mingcong Yang, Ziyu Huang, Kamoran Tuerhong, Yue Zu, Ying Xie, Xuehui Hu, Qianyu Zhang, Ping He, Nannan Huang, Rong Zhang, Yuzhou Li, Sheng Yang   +13 more
wiley   +1 more source

Paresthesia in Spinal Anesthesia [PDF]

, 2012
Spinal anesthesia is induced by injecting small amounts of local anesthetic into the cerebrospinal fluid (CSF), which solution must be capable of blocking nerve paths, and non-toxic, that is, it should not hinder the proper functioning of the bulbar centers, or interfere with the metabolic processes of the more important organs.
Luiz Eduardo Imbelloni, Marildo A. Gouveia   +1 more
openaire   +3 more sources

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

Advanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang, Guofu Zhang, Yizhou Zhu, Jingcheng Wang, Xinmin Feng, Wenyong Fei, Jihang Dai, Le Hu, Yi Zhang, Jun Cai, Binjia Ruan, Yue Jin, Fanhao Wei, Gang Lu, Dongan Wang, Jason Pui Yin Cheung, Graham Ka Hon Shea, Hao Chen, Kelvin Wai Kwok Yeung, Lei Wang, Yongxiang Wang   +20 more
wiley   +1 more source

Shivering Management in Spinal Anesthesia: Evaluating the Role of Ketamine: A Narrative Review

Archives of Anesthesia and Critical Care
Background: Shivering is one of the most prevalent known complications due to dysregulation in the thermoregulatory system following regional anesthesia, with an incidence of 65%, leading to unpleasant outcomes and decreased patient satisfaction ...
Siavash Sangi, Mehrdad Mesbah Kiaei, Shahnam Sedigh Maroufi, Maryam Aligholizadeh, Parisa Moradimajd, Azam Saei   +5 more
doaj   +1 more source

The effect of teaching on the completeness of the anesthesia record charts for obstetric subarachnoid blocks in a low resource area hospital

Journal of Obstetric Anaesthesia and Critical Care, 2015
Background: Spinal anesthesia is a widely practiced anesthetic technique for cesarean delivery. Record charting and keeping during obstetric spinal anesthesia demand accuracy and completeness for patient′s safety, medico-legal and research purposes. This
Simeon Olugbade Olateju, Anthony Taiwo Adenekan, Afolabi Muyiwa Owojuyigbe   +2 more
doaj   +1 more source