Results 31 to 40 of about 858,923 (311)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Vital sign monitoring with continuous pulse oximetry and wireless clinical notification after surgery (the VIGILANCE pilot study)—a randomized controlled pilot trial

Pilot and Feasibility Studies, 2019
Background Respiratory depression is a serious perioperative complication associated with morbidity and mortality. Recently, technology has become available to wirelessly monitor patients on regular surgical wards with continuous pulse oximetry and ...
James E. Paul, Matthew A. Chong, Norman Buckley, Prathiba Harsha, Harsha Shanthanna, Antonella Tidy, Diane Buckley, Anne Clarke, Christopher Young, Timothy Wong, Thuvaraha Vanniyasingam, Lehana Thabane   +11 more
doaj   +1 more source

A case of left ventricular free wall rupture after insertion of an IMPELLA® left ventricular assist device diagnosed by transesophageal echocardiography

JA Clinical Reports, 2021
Background The IMPELLA® is a minimally invasive left ventricular assist device. We report a case in which transesophageal echocardiography (TEE) was useful in diagnosis of left ventricular rupture after IMPELLA® insertion. Case presentation A 75-year-old
Akito Mizuno, Shuji Kawamoto, Shuji Uda, Kenichiro Tatsumi, Chikashi Takeda, Tomoharu Tanaka, Kazuhiko Fukuda   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Propofol Anesthesia

Veterinary Clinics of North America: Small Animal Practice, 1999
Although questions may still remain regarding the use of this unique sedative-hypnotic drug with anesthetic properties in high-risk patients, our studies have provided cardiopulmonary and neurological evidence of the efficacy and safety of propofol when used as an anesthetic under normal and selected impaired conditions in the dog. 1.
Short C. E., BUFALARI, Antonello
openaire   +3 more sources

Identification of Sleep Medicine and Anesthesia Core Topics for Anesthesia Residency: A Modified Delphi Technique Survey

, 2021
BACKGROUND: Sleep disorders affect up to 25% of the general population and are associated with increased risk of adverse perioperative events. The key sleep medicine topics that are most important for the practice of anesthesiology have not been well ...
Wong, J, Singh, M, Auckley, D, Jonsson, Fagerlund M,, Gali, B, Joshi, GP, Charchaflieh, JG, Berezin, L, Nagappa, M, Clivatti, J   +9 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Comparison of two Norepinephrine rescue bolus for Management of Post-spinal Hypotension during Cesarean Delivery: a randomized controlled trial

BMC Anesthesiology, 2020
Background Data on the best norepinephrine bolus dose for management of hypotension are limited. The aim of this study was to compare the efficacy and safety of two norepinephrine bolus doses in the rescue management of maternal hypotension during ...
Yasmin S. Hassabelnaby, Ahmed M. Hasanin, Nada Adly, Maha M. A. Mostafa, Sherin Refaat, Eman Fouad, Mohamed Elsonbaty, Hazem A. Hussein, Mohamed Mahmoud, Yaser M. Abdelwahab, Ahmed Elsakka, Sarah M. Amin   +11 more
doaj   +1 more source

Department of Anesthesia. University of Iowa. Fall 2008. [PDF]

, 2008
University of Iowa Department of Anesthesia ...

core  

Regional Anesthesia for Bilateral Carpal Tunnel Release [PDF]

, 2018
Carpal Tunnel Syndrome is the most common nerve entrapment neuropathy with over 60% of diagnosed patients presenting with bilateral median nerve involvement.  Bilateral upper extremity surgery presents unique anesthesia challenges, yet surgeons are ...
Varela, DNP, CRNA, Debra S., Newman, DNAP, CRNA, Johanna, Valdes, DNP, CRNA, Jorge A.   +2 more
core   +1 more source