Results 31 to 40 of about 1,024,962 (256)

Unveiling age-independent spectral markers of propofol-induced loss of consciousness by decomposing the electroencephalographic spectrum into its periodic and aperiodic components

Frontiers in Aging Neuroscience, 2023
BackgroundInduction of general anesthesia with propofol induces radical changes in cortical network organization, leading to unconsciousness. While perioperative frontal electroencephalography (EEG) has been widely implemented in the past decades ...
Sophie Leroy, Sebastian Major, Sebastian Major, Sebastian Major, Viktor Bublitz, Jens P. Dreier, Jens P. Dreier, Jens P. Dreier, Jens P. Dreier, Jens P. Dreier, Susanne Koch   +10 more
doaj   +1 more source

Comparison of sevoflurane and ketamine for anesthetic induction in children with congenital heart disease

, 2021
Background: Sevoflurane is widely used in pediatric anesthesia for induction. Ketamine has been preferred in pediatric cardiovascular anesthesia. Aim of this study was to compare the hemodynamic effects and the speed of ketamine and sevoflurane for ...
Kartal, Umut, Camci, Emre, Tugrul, Mehmet, Sungur, Mukadder, Ulke, Zerrin Sungur   +4 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Does Intravenous Fentanyl Affect Apgar Scores and Umbilical Vessel Blood Gas Parameters in Cesarean Section Under General Anesthesia? [PDF]

Acta Medica Iranica, 2011
The administration of opioids during induction of general anesthesia is a matter of challenge in obstetric anesthesia. The aim of this study was to investigate the effects of intravenous fentanyl before induction of general anesthesia on the"1st and 5th ...
Maziyar Maghsoudloo, Negar Eftekhar, Mohammad Ali Noyan Ashraf, Zahid Husain Khan, Homeira Peiravy Sereshkeh   +4 more
doaj   +1 more source

Anesthesia protocol for ear surgery in Wistar rats (animal research)

Animal Models and Experimental Medicine, 2022
Objective To formulate an anesthesia protocol for safe and satisfactory anesthesia for ear surgery in rats. Methods The rats were anesthetized with xylazine (10 mg/kg body weight) and ketamine at doses of 80, 50, 40, and 30 mg/kg body weight or with ...
Abhijeet Bhatia, Pranjal Pratim Saikia, Barilin Dkhar, Haphidasara Pyngrope   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Comparison of remimazolam tosylate and sevoflurane for anesthesia induction with preserved spontaneous respiration during tracheal intubation: a prospective, single-center, randomized controlled trial

Perioperative Medicine
Background and objectives Remimazolam tosylate is a novel anesthetic agent known for its rapid onset, non-irritating and non-polluting properties, effective sedation with minimal respiratory depression, short duration of action, and suitability for ...
Yu Hong, Shiyu Meng, Jiayi Liu, Qiong Zhao, Jun Peng, Yuqing Chen   +5 more
doaj   +1 more source

Reduction of Nonoperative Time Using the Induction Room, Parallel Processing, and Sugammadex: A Randomized Clinical Trial [PDF]

, 2022
BACKGROUND: An important variable in the operating room is the nonoperative time (NOT), the time between skin closure on a previous case and skin incision on the following case.
Bouez, Joanna, Said Tarraf, Tarraf, Said, Bouez, Joanna N., Shebbo, Fadia M., Shebbo, Fadia, Carol Abi Shadid, Arwa Bou Ali, Joanna Bouez, Cynthia Karam, Bou Ali, Arwa, Abi Shadid, Carol, Bou Ali, Arwa W., Kaddoum, Roland, Aouad, Marie T., Roland Kaddoum, Fadia M. Shebbo, Karam, Cynthia, Marie T. Aouad, Kaddoum, Roland N., Karam, Cynthia J.   +20 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source