Results 51 to 60 of about 262,695 (299)

A Cost Analysis of Carpal Tunnel Release Surgery Performed Wide Awake versus under Sedation. [PDF]

, 2018
BACKGROUND: Hand surgery under local anesthesia only has been used more frequently in recent years. The purpose of this study was to compare perioperative time and cost for carpal tunnel release performed under local anesthesia ( wide-awake local ...
Al Youha, Apfel, Carroll, Codding, Davison, Hill, Ketonis, Kim, Lalonde, Lalonde, Lalonde, Lalonde, Lalonde, Lalonde, Mckee, Nodwell, Raft, Ruxasagulwong, Stead, Tang, Teo, Vinycomb, Young, Zhang   +23 more
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]

, 2013
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken, Cianchetti, Flor A., Fan, Xiang, Förch, Christian, Lauer, Arne, Leyen, Klaus van, Lo, Eng H., Mandeville, Emiri, Rosidi, Nathanael L., Schaffer, Chris B., Schlunk, Frieder, Steinmetz, Helmuth, Wang, Xiaoying, Yigitkanli, Kazim   +13 more
core   +5 more sources

The safety and efficacy of remimazolam tosylate for induction and maintenance of general anesthesia in pediatric patients undergoing elective surgery: Study protocol for a multicenter, randomized, single-blind, positive-controlled clinical trial

Frontiers in Pharmacology, 2023
Introduction: Remimazolam is an ultra-short-acting benzodiazepine sedative agent commonly used in general anesthesia, procedural sedation, and intensive care unit (ICU) sedation.
Yu-Bo Fang, Cheng-Yu Wang, Yu-Qing Gao, Yu-Hang Cai, Jia Chen, Xu-Lin Zhang, Le-Qi Dong, Wang-Ning Shang-Guan, Hua-Cheng Liu   +8 more
doaj   +1 more source

Anesthesia for cystotomy in a dog with pancreatitis and a portosystemic shunt [PDF]

, 2010
A 21-month-old Cocker spaniel with a portosystemic shunt, a moderate thrombocytopenia and a history of pancreatitis, was anesthetized for a cystotomy to remove bladder polyps and stones.
Brearley, JC, Gasthuys, Frank, Schauvliege, Stijn, Seymour, C   +3 more
core   +1 more source

The determinants of propofol induction time in anesthesia [PDF]

Korean Journal of Anesthesiology, 2013
The required dose of anesthetics is generally smaller in patients with low cardiac output (CO). A high CO decreases the blood concentration of anesthetics during induction and maintenance of anesthesia. However, a high CO may also shorten the delivery time of anesthetics to the effect site, e.g. the brain. We assessed the time required for induction of
Yushi U. Adachi, Maiko Satomoto, Hideyuki Higuchi, Kazuhiko Watanabe   +3 more
openaire   +3 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Anesthesia protocol for ear surgery in Wistar rats (animal research)

Animal Models and Experimental Medicine, 2022
Objective To formulate an anesthesia protocol for safe and satisfactory anesthesia for ear surgery in rats. Methods The rats were anesthetized with xylazine (10 mg/kg body weight) and ketamine at doses of 80, 50, 40, and 30 mg/kg body weight or with ...
Abhijeet Bhatia, Pranjal Pratim Saikia, Barilin Dkhar, Haphidasara Pyngrope   +3 more
doaj   +1 more source

Direct Current Auditory Evoked Potentials During Wakefulness, Anesthesia, and Emergence from Anesthesia [PDF]

, 2001
Direct current auditory evoked potentials (DC-AEPs) are a sensitive indicator of depth of anesthesia in ani-mals. However, they have never been investigated in humans. To assess the potential usefulness of DC-AEPs as an indicator of anesthesia in humans,
Bauer, Herbert, Fitzgerald, Robert, Lamm, Claus, Oczenski, Wolfgang, Stimpfl, Thomas, Vycudilik, Walter   +5 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source