Results 61 to 70 of about 262,695 (299)

GABAergic neurons in the dorsomedial hypothalamus regulate states of consciousness in sevoflurane anesthesia

iScience, 2023
Summary: The neural inhibitory gamma-aminobutyric acid (GABA) system in the regulation of anesthetic consciousness is heterogeneous, and the medial hypothalamus (MH), consisting of ventromedial hypothalamus (VMH) and dorsomedial hypothalamus (DMH), plays
Yanfeng Wang, Yanping Song, Li Tong, Lu Wang, Jiangbei Cao, Gang Qin, Xingyang Liu, Weidong Mi, E. Wang, Yongxin Guo   +9 more
doaj   +1 more source

Sevoflurane induction of anesthesia in elderly patients [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2003
SpO2 was greater than 97%; 3) a tube exchanger catheter was inserted through the ET; 4) the LMA® and ET were withdrawn together; 5) an ET size ID 8 mm was threaded over the tube exchanger. With an unhurried approach we achieved safe control of the airway, with adequate oxygenation and mechanical ventilation in a few minutes.
Marie-José, Colas, René, Martin, Valérie, Cardinal   +2 more
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Cardiac arrest in a child during a combined general epidural anesthesia procedure [PDF]

, 2005
An increased risk of perioperative cardiac arrest in children, in comparison to adults, has been recognized. A number of factors associated with perioperative cardiac arrest have been identified, including young age, comorbidities, and emergency ...
Prabakti, Yudhi, Siahaan, Edwin MP, Sidhartani,, M, Soemantri,, A, Soenarjo, Soenarjo   +4 more
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Lung ultrasound assessment of atelectasis following different anesthesia induction techniques in pediatric patients: a propensity score-matched, observational study

Journal of Anesthesia, Analgesia and Critical Care
Introduction Atelectasis is a well-documented complication in pediatric patients undergoing general anesthesia. Its incidence varies significantly based on surgical procedures and anesthesia techniques.
Anna Camporesi, Giulia Roveri, Luigi Vetrugno, Danilo Buonsenso, Valentina De Giorgis, Sara Costanzo, Ugo Maria Pierucci, Gloria Pelizzo   +7 more
doaj   +1 more source

A New/Old Look at the Problem of Anesthetic Maintenance of Colonoscopy

Общая реаниматология, 2012
Objective: to compare different modes of anesthesia maintenance for colonoscopy on the basis of internal audit of critical incidents. Subjects and methods. This investigation was conducted at the V. A. Negovsky Research Institute of General Reanimatology,
M. V. Gabitov, O. A. Grebenchikov, A. V., Mironenko, Yu. V. Skripkin, S. V. Korobkin, V. V. Likhvantsev   +5 more
doaj   +1 more source

The use of tricaine methanesulfonate, clove oil, metomidate, and 2-phenoxyethanol for anesthesia induction in alewives (Alosa pseudoharengus) [PDF]

, 2015
Anesthetics are widely used in routine aquaculture operations to immobilize animals for tagging, spawning, handling, and vaccination. A number of anesthetics are currently available for finfish, but their efficacy and optimal dosage is highly species ...
Watson, Mark Thomas
core   +2 more sources