Results 201 to 210 of about 404,043 (380)

Low‐intervention clinical trials in Spain: Do they progress?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza   +4 more
wiley   +1 more source

Using machine learning techniques to develop forecasting algorithms for postoperative complications: Protocol for a retrospective study [PDF]

open access: yes, 2018
Avidan, Michael Simon   +11 more
core   +2 more sources

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Hemolysis Detected Following the Preparation and Collection of Blood in a Porcine Model Using a Syringe‐Based Aspiration Thrombectomy System for Autotransfusion

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Autologous transfusion of filtered, unwashed blood is a technique to mitigate the effects of blood loss during mechanical thrombectomy, but the degree of hemolysis resulting from this approach and guidance for blood return in this setting is not well understood.
Suhail Dohad   +3 more
wiley   +1 more source

Anesthesiology [PDF]

open access: yes, 2006
佐々木 利佳   +10 more
core   +1 more source

[Recommendations for the perioperative use of dipyrone : Expert recommendation of the working group on acute pain of the German Pain Society, the scientific working group on pain medicine of the German Society for Anesthesiology and Intensive Care Medicine and the surgical working group on acute pain of the German Society for Surgery with participation of representatives of the Drug Commission of the German Medical Association].

open access: green, 2019
Ulrike M. Stamer   +20 more
openalex   +1 more source

Anesthesiology [PDF]

open access: yes, 2005
佐々木 利佳   +9 more
core   +1 more source

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