A quantitative model for refilling of the sarcoplasmic reticulum during vascular smooth muscle asynchronous [Ca2+] oscillations [PDF]
Cell Calcium 42, 565-75 (2007), 2006 We have developed a quantitative model for the creation of cytoplasmic Ca2+ gradients near the inner surface of the plasma membrane (PM). In particular we simulated the refilling of the sarcoplasmic reticulum (SR) via PM-SR junctions during asynchronous [Ca2+] oscillations in smooth muscle cells of the rabbit inferior vena cava.
arxiv +1 more source
A bibliometric search of citation classics in anesthesiology [PDF]
, 2011 BACKGROUND: Articles cited counts are catalogued and help identify landmark papers. This study provides a citation classics of anesthesiology literature using the framework of subspecialties to provide a review of well-developed areas of research in ...
Andrew L Rosenberg +3 more
core +2 more sources
Machine learning-based analysis of hyperspectral images for automated sepsis diagnosis [PDF]
arXiv, 2021 Sepsis is a leading cause of mortality and critical illness worldwide. While robust biomarkers for early diagnosis are still missing, recent work indicates that hyperspectral imaging (HSI) has the potential to overcome this bottleneck by monitoring microcirculatory alterations.
arxiv
Artificial Intelligence and Machine Learning in Anesthesiology.
Anesthesiology, 2019 Commercial applications of artificial intelligence and machine learning have made remarkable progress recently, particularly in areas such as image recognition, natural speech processing, language translation, textual analysis, and self-learning ...
C. Connor
semanticscholar +1 more source
Diversity, equity, and inclusion in anesthesiology
International Anesthesiology Clinics, 2021 Disparities in population health are driven by a dynamic set of factors, known as social determinants of health. Although individualsmay not have a direct influence over the upstream social factors (poverty, homelessness, racism) that drive disparities ...
S. Estime +5 more
semanticscholar +1 more source
Anesthesiology, 2019 WHAT WE ALREADY KNOW ABOUT THIS TOPIC Burnout has been identified in approximately 50% of residents and practicing physicians WHAT THIS ARTICLE TELLS US THAT IS NEW: Based on survey data from 2013 to 2016, the prevalence of burnout, distress, and ...
Huaping Sun +5 more
semanticscholar +1 more source
Offline reinforcement learning with uncertainty for treatment strategies in sepsis [PDF]
arXiv, 2021 Guideline-based treatment for sepsis and septic shock is difficult because sepsis is a disparate range of life-threatening organ dysfunctions whose pathophysiology is not fully understood. Early intervention in sepsis is crucial for patient outcome, yet those interventions have adverse effects and are frequently overadministered.
arxiv
Structural network heterogeneities and network dynamics: a possible dynamical mechanism for hippocampal memory reactivation [PDF]
, 2006 The hippocampus has the capacity for reactivating recently acquired memories [1-3] and it is hypothesized that one of the functions of sleep reactivation is the facilitation of consolidation of novel memory traces [4-11]. The dynamic and network processes underlying such a reactivation remain, however, unknown.
arxiv +1 more source
An approach to study recruitment/derecruitment dynamics in a patient-specific computational model of an injured human lung [PDF]
arXiv, 2022 We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an anatomically accurate, spatially resolved model of respiratory system mechanics, and the relation of these dynamics
arxiv
Comparison of the qCON and qNOX indices for the assessment of unconsciousness level and noxious stimulation response during surgery [PDF]
, 2016 The objective of this work is to compare the performances of two electroencephalogram based indices for detecting loss of consciousness and loss of response to nociceptive stimulation.
Agustí, Mercé +8 more
core +2 more sources