Results 51 to 60 of about 296,248 (300)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Valoración de implicaciones para la formación en Residencia Médica de Anestesiología

Cuaderno de Pedagogía Universitaria, 2014
Se presenta una sistematización de los procesos de enseñanza-aprendizaje de la residencia médica de Anestesiología en uno de los hospitales universitarios avalada por la Pontificia Universidad Católica Madre y Maestra.
Evangelina Hernández
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Comparing the Postoperative Sore Throat Incidence and Hemodynamic Changes after Using Macintosh and GlideScope Laryngoscopes and Laryngeal Mask Airway

The Journal of Qazvin University of Medical Sciences, 2020
Background Studies have shown that postoperative sore throat (POST) is the most common complication of tracheal intubation; however, its actual incidence and extent are not well documented.
Mohammad Ali Masoumifar, Mahdi Ebtehaj, Hamid Kayalha, Ali Akbar Shafikhani   +3 more
doaj   +1 more source

This Month in Anesthesiology [PDF]

Anesthesiology, 2020
  +17 more sources

January issue of the Emirati Journal of Anesthesiology

, 2023
The first (January 2024) issue of the Emirati Journal of Anesthesiology (EJoAn) which is the official journal of the Emirati Society of Anesthesiology (ESoAn.org).
Mhamad AlHashimi (17695044)
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Anesthesiology residents’ perspective about good teaching – a qualitative needs assessment

GMS German Medical Science, 2014
[english] Background: Germany, like many other countries, will soon have a shortage of qualified doctors. One reason for the dissatisfaction amongst medical residents are the relatively unstructured residency training programs despite increasing ...
Ortwein, Heiderose, Blaum, Wolf E., Spies, Claudia D.   +2 more
doaj   +1 more source

Current situation of pediatric anesthesiology training in Colombia

Surgery is a key pillar in medical care, and both the surgical as well as the anesthetic components are essential within the health systems in countries of all levels of development.
Chávez N.R., Hernández J.S.C.
core   +1 more source