Results 181 to 190 of about 343,216 (264)

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

open access: yesAdvanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng   +13 more
wiley   +1 more source

Effectiveness of Combining Lidocaine and Ropivacaine on the Duration of Analgesia and Anesthesia of an Infraclavicular Brachial Plexus Block. [PDF]

open access: yesLocal Reg Anesth
Steensbæk MT   +8 more
europepmc   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

open access: yesAdvanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang   +8 more
wiley   +1 more source

Fascial plane blocks as the main anesthetic method: A narrative review. [PDF]

open access: yesSaudi J Anaesth
Tulgar S   +6 more
europepmc   +1 more source

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

open access: yesAdvanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier   +4 more
wiley   +1 more source

Development of Carbon‐11 Labeled Pyrimidine Derivatives as Novel Positron Emission Tomography (PET) Agents Enabling Brain Sigma‐1 Receptor Imaging

open access: yesAdvanced Science, EarlyView.
Novel carbon‐11 labeled pyrimidine derivatives are developed as PET imaging probes for visualizing sigma‐1 receptors in the brain. [11C]CNY‐01 demonstrates superior brain uptake and binding specificity in both rodents and non‐human primates. The study reveals decreased sigma‐1 receptor expression in Alzheimer's disease, offering a promising tool for ...
Ping Bai   +12 more
wiley   +1 more source

Local Anesthetics

open access: yes, 2020
M., Whizar-Lugo, Víctor   +3 more
openaire   +3 more sources

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